Characteristics | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
DM II group (n = 26) | Non-DM II group (n = 52) | P value | (95% CI) | P value | |
Age (years) | 57.31 ± 14.27 | 52.20 ± 15.84 | 0.173 |  |  |
Sex: Male (n %) | 12(46.15%) | 29(55.77%) | 0.423 | Â | Â |
Rural area (n %) | 21(80.77%) | 44(84.61%) | 0.667 | Â | Â |
Underlying conditions | |||||
 Respiratory diseases (n %) | 3(11.53%) | 7(13.46%) | 0.811 |  |  |
 Chronic kidney diseases (n %) | 2(7.69%) | 4(7.69%) | 1.000 |  |  |
 Hepatitis B (n %) | 3(11.53%) | 3(5.77%) | 0.367 |  |  |
 Hypertension (n %) | 4(15.38%) | 2(3.85%) | 0.071 | (0.026,1.109) | 0.064 |
 Autoimmune disease (n %) | 3(11.53%) | 4(7.69%) | 0.575 |  |  |
 Hematology and oncology (n %) | 0 | 1(1.92%) | 0.477 |  |  |
 The duration before confirmed diagnosis (days) | 27.00 ± 23.13 | 26.30 ± 18.93 | 0.501 |  |  |
 Duration of DM II course (years) | 4.20 ± 3.34 | – | – |  |  |
Clinical parameters | |||||
 Fever (n %) | 21(80.77%) | 39(75.00%) | 0.569 |  |  |
 Headache (n %) | 25(96.15%) | 50(96.15%) | 1.000 |  |  |
 Nausea/Vomiting (n %) | 16(61.54%) | 25(48.07%) | 0.262 |  |  |
 Vision disorders (n %) | 8(28.54%) | 6(11.54%) | 0.038* | (0.056,0.705) | 0.012* |
 Auditory symptoms (n %) | 2(7.69%) | 4(7.69%) | 1.000 |  |  |
 Seizure (n %) | 3(11.54%) | 3(5.77%) | 0.367 |  |  |
 Conscious disturbance (n %) | 8(30.77%) | 9(17.31%) | 0.175 |  |  |
CSF examinations | |||||
 Opening pressure (mmH2O) | 271.54 ± 100.78 | 234.23 ± 105.98 | 0.125 |  |  |
 CSF protein (mg/l) | 1027.62 ± 594.16 | 705.72 ± 373.88 | 0.031* | (1.000,1.002) | 0.016* |
 CSF glucose (mmol/l) | 2.08 ± 1.01 | 2.30 ± 1.41 | 0.250 |  |  |
 Positive India ink stain (n %) | 19(73.08%) | 40(76.92%) | 0.709 |  |  |
 Positive cryptococcal antigen (n %) | 25(96.15%) | 50(96.13%) | 1.000 |  |  |
 Positive culture result (n %) | 17(65.38%) | 32(61.54%) | 0.740 |  |  |
Brain images (CT or MRI) | |||||
 Meningeal enhancement (n %) | 10(38.46%) | 22(42.30%) | 0.745 |  |  |
 Hydrocephalus (n %) | 2(7.69%) | 4(7.69%) | 1.000 |  |  |
 Cerebral infarction (n %) | 4(15.38%) | 6(11.54%) | 0.632 |  |  |
 Abscess (n %) | 2(7.69%) | 2(3.84%) | 0.468 |  |  |
 Normalea (n %) | 8(30.77%) | 18(34.62%) | 0.734 |  |  |