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Table 1 Clinical characteristics of children with single B. pertussis infection and children with B. pertussis-RSV coinfection

From: Clinical impact of respiratory syncytial virus infection on children hospitalized for pertussis

Characteristics Pertussis Group (n = 37) Coinfection Group (n = 43) P value
Demographics
 Male, n (%) 18 (49%) 24 (59%) 0.522
 Age, months, median (IQR) 4.03 (1.85–5.05) 4.57 (3.40–6.03) 0.048
 Body weight, kg, median (IQR) 6.60 (5.40–7.75) 6.70 (5.80–7.80) 0.732
 Preterm birth, n (%) 3 (8%) 7 (16%) 0.271
Pertussis vaccination, n (%) 18 (49%) 24 (59%) 0.522
Symptoms and signs
 Paroxysms of coughing, n (%) 37 (100%) 43 (100%)
 Inspiratory whooping, n (%) 11 (30%) 19 (44%) 0.183
 Cyanosis, n (%) 17 (46%) 19 (44%) 0.875
 Wheezes on auscultation, n (%) 5 (14%) 17 (40%) 0.009
 Rales on auscultation, n (%) 5 (14%) 15 (35%) 0.028
 Pneumonia, n (%) 16 (43%) 16 (37%) 0.583
Laboratory tests
 WBC count, 109/L, median (IQR) 16.19 (13.37–19.69) 14 .04 (11.92–18.43) 0.110
 Lymphocyte count, 109/L, median (IQR) 10.38 (8.50–14.68) 9.29 (8.27–13.76) 0.364
Treatment and hospitalization
 β-lactam antibiotic use, n (%) 2 (5%) 9 (21%) 0.044
 ICU admission, n 1 0
 Readmission, n (%) 4 (11%) 17 (40%) 0.004
 Hospital stay, days, median (IQR) 7 (6–10) 10 (7–15) 0.002
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