Table 1 Clinical characteristics of children with single B. pertussis infection and children with B. pertussis-RSV coinfection
From: Clinical impact of respiratory syncytial virus infection on children hospitalized for pertussis
Characteristics | Pertussis Group (n = 37) | Coinfection Group (n = 43) | P value |
|---|---|---|---|
Demographics | |||
Male, n (%) | 18 (49%) | 24 (59%) | 0.522 |
Age, months, median (IQR) | 4.03 (1.85–5.05) | 4.57 (3.40–6.03) | 0.048 |
Body weight, kg, median (IQR) | 6.60 (5.40–7.75) | 6.70 (5.80–7.80) | 0.732 |
Preterm birth, n (%) | 3 (8%) | 7 (16%) | 0.271 |
Pertussis vaccination, n (%) | 18 (49%) | 24 (59%) | 0.522 |
Symptoms and signs | |||
Paroxysms of coughing, n (%) | 37 (100%) | 43 (100%) | – |
Inspiratory whooping, n (%) | 11 (30%) | 19 (44%) | 0.183 |
Cyanosis, n (%) | 17 (46%) | 19 (44%) | 0.875 |
Wheezes on auscultation, n (%) | 5 (14%) | 17 (40%) | 0.009 |
Rales on auscultation, n (%) | 5 (14%) | 15 (35%) | 0.028 |
Pneumonia, n (%) | 16 (43%) | 16 (37%) | 0.583 |
Laboratory tests | |||
WBC count, 109/L, median (IQR) | 16.19 (13.37–19.69) | 14 .04 (11.92–18.43) | 0.110 |
Lymphocyte count, 109/L, median (IQR) | 10.38 (8.50–14.68) | 9.29 (8.27–13.76) | 0.364 |
Treatment and hospitalization | |||
β-lactam antibiotic use, n (%) | 2 (5%) | 9 (21%) | 0.044 |
ICU admission, n | 1 | 0 | – |
Readmission, n (%) | 4 (11%) | 17 (40%) | 0.004 |
Hospital stay, days, median (IQR) | 7 (6–10) | 10 (7–15) | 0.002 |