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Table 1 Demographic characteristics and factors associated with drug resistance (n = 1151)

From: HIV drug resistance and HIV transmission risk factors among newly diagnosed individuals in Southwest China

Variables N (%) TDR Crude OR
(95% CI)
p Adjusted OR (95% CI)a p
Age
  < 35 508 (44.1) 26 (31.3) 1   1  
  ≥ 35 643 (55.9) 57 (68.7) 1.77 (1.09–2.86) 0.020 1.77 (0.9–3.52) 0.093
Marital status
 Married 479 (41.6) 34 (41.0) 1   1  
 Unmarried 534 (46.4) 38 (45.8) 0.97 (0.6–1.58) 0.916 2.41 (1.23–4.71) 0.011
 Divorced/widowed 126 (11.0) 9 (10.8) 1.01 (0.47–2.16) 0.986   
 Unknown 12 (1.0) 2 (2.4) 2.62 (0.55–12.43) 0.226   
Educational level
 College and above 336 (29.2) 19 (22.9) 1   1  
 High school or technical school 225 (19.6) 12 (14.5) 0.86 (0.4–1.84) 0.693 0.84 (0.38–1.89) 0.673
 Junior high school/below 590 (51.2) 52 (62.6) 1.61 (0.94–2.78) 0.085 1.07 (0.53–2.19) 0.844
Ethnicity
 Han 601 (52.2) 43 (51.8) 1    
 Zhuang 483 (41.9) 33 (39.8) 0.98 (0.61–1.57) 0.920   
 Other 68 (5.9) 7 (8.4) 1.55 (0.67–3.61) 0.306   
Infection route
 MSM 405 (35.2) 18 (21.7) 1   1  
 Heterosexual 693 (60.2) 62 (74.7) 0.45 (0.26–0.77) 0.004 0.61 (0.3–1.23) 0.167
 Other 53 (4.6) 3 (3.6) 0.61 (0.19–2.02) 0.418   
Sex
 Male 919 (79.8) 63 (75.9) 1    
 Female 232 (20.2) 20 (24.1) 1.3 (0.77–2.21) 0.323   
Subtype
 CRF01_AE 485 (42.1) 33 (39.8) 1   1  
 CRF07_BC 356 (30.9) 14 (16.9) 0.52 (0.27–1.00) 0.050 0.57 (0.29–1.14) 0.113
 CRF08_BC 183 (15.9) 25 (30.1) 2.19 (1.26–3.78) 0.005 2.03 (1.13–3.64) 0.018
 CRF55_01B 79 (6.9) 3 (3.6) 0.53 (0.16–1.78) 0.308 0.57 (0.17–1.97) 0.405
 Otherb 48 (4.2) 8 (9.6) 2.74 (1.19–6.33) 0.018 2.73 (1.14–6.51) 0.024
Year of diagnosis
 2016 348 (30.2) 30 (36.1) 1    
 2017 422 (36.7) 32 (38.6) 0.9 (0.54–1.52) 0.701   
 2018 381 (33.1) 21 (25.3) 0.64 (0.36–1.15) 0.135   
  1. aAdjusted for age, marital status, educational level, infection route, and subtype
  2. bOther includes B subtype (N = 17, transmitted drug resistance = 7) and other subtype (N = 31, transmitted drug resistance = 1)
  3. DR drug resistance, OR odds ratio, CI confidence interval, MSM men who have sex with men, CRF circulating recombinant form