From: Physical disabilities caused by leprosy in 100 million cohort in Brazil
Grade 1 | Grade 2 | |||
---|---|---|---|---|
ORcrudea (95%CI) | ORadjb,c (95%CI) | ORcrudea (95%CI) | ORadjb,c (95%CI) | |
(N = 5,026) | (N = 5,026) | (N = 1,444) | (N = 1,444) | |
Individual characteristics | ||||
Age | ||||
Up to 15 years old | 1.00 | 1.00 | 1.00 | 1.00 |
> 15 years old | 3.41 (3.01–3.87) | 2.39 (2.06–2.77) | 3.28 (2.63–4.11) | 1.95 (1.51–2.50) |
Sex | ||||
Male | 1.00 | 1.00 | 1.00 | 1.00 |
Female | 0.62 (0.58–0.66) | 0.81 (0.75–0.88) | 0.48 (0.38–0.48) | 0.61 (0.53–0.70) |
Schooling | ||||
No education/Pre-school | 1.60 (0.86–2.94) | 1.64 (1.40–1.93) | 3.83 (0.93–15.88) | 1.91 (1.44–2.53) |
Primary School (1–5 years) | 1.30 (0.71–2.38) | 1.48 (1.28–1.70) | 2.67 (0.65–11.04) | 1.64 (1.27–2.12) |
High School (6–9 years) | 0.95 (0.52–1.74) | 1.28 (1.10–1.48) | 1.82 (0.44–7.55) | 1.31 (1.00–1.72) |
Senior High School (10–12 years) | 0.72 (0.39–1.32) | – | 1.27 (0.30–5.34) | – |
Higher Education (≥12 years) | 1.00 | 1.00 | 1.00 | 1.00 |
Work condition | ||||
Employed | 1.00 | 1.00 | 1.00 | 1.00 |
Unemployed | 1.06 (0.98–1.16) | 1.19 (1.06–1.32) | 1.01 (0.86–1.18) | 1.47 (1.23–1.74) |
Unemployed but currently studying | 1.34 (1.23–1.45) | 1.13 (1.03–1.24) | 1.59 (1.39–1.81) | 1.15 (0.98–1.35) |
Household characteristics | ||||
Region of residence | ||||
North | 0.55 (0.46–0.66) | 0.91 (0.72–1.15) | 0.32 (0.25–0.42) | 0.53 (0.39–0.72) |
Northeast | 0.49 (0.41–0.58) | 0.81 (0.64–1.01) | 0.31 (0.24–0.39) | 0.53 (0.39–0.71) |
Southeast | 0.70 (0.58–0.85) | 1.06 (0.84–1.33) | 0.58 (0.45–0.76) | 0.80 (0.59–1.08) |
South | 1.00 | 1.00 | 1.00 | 1.00 |
Midwest | 0.65 (0.54–0.78) | 0.86 (0.68–1.09) | 0.38 (0.29–0.49) | 0.50 (0.36–0.68) |
Area of residence | ||||
Urban | 1.00 | 1.00 | 1.00 | 1.00 |
Rural | 1.17 (1.08–1.27) | 1.14 (1.04–1.26) | 1.12 (0.98–1.28) | 1.05 (0.89–1.24) |
Household density | ||||
≤ 0.5 inhab/room | 1.00 | 1.00 | 1.00 | 1.00 |
0.5–0.75 inhab/room | 0.71 (0.65–0.78) | 0.87 (0.78–0.98) | 0.66 (0.57–0.78) | 0.96 (0.80–1.16) |
0.75–1.00 inhab/room | 0.68 (0.63–0.75) | 0.87 (0.78–0.97) | 0.62 (0.53–072) | 0.85 (0.71–1.03) |
> 1.00 inhab/room | 0.62 (0.57–0.68) | 0.79 (0.71–0.88) | 0.68 (0.59–0.79) | 1.04 (0.87–1.23) |
High-burden cluster municipality | ||||
No | 1.00 | 1.00 | 1.00 | 1.00 |
Yes | 0.79 (0.74–0.85) | 0.85 (0.78–0.93) | 0.58 (0.52–0.65) | 0.67 (0.58–0.78) |
Clinical characteristics | ||||
WHO operational classification | ||||
Paucibacillary | 1.00 | 1.00 | 1.00 | 1.00 |
Multibacillary | 4.36 (4.04–4.71) | 3.50 (3.13–3.92) | 10.70 (8.90–12.87) | 8.22 (6.51–10.38) |
Presence of lesions | ||||
No | 1.00 | 1.00 | 1.00 | 1.00 |
Yes | 2.56 (2.38–2.76) | 1.12 (1.02–1.24) | 3.44 (3.15–3.93) | 1.03 (0.88–1.20) |