| |
Adjustedb analysis
|
Multivariable analysis
|
Point
|
|---|
|
Parameters
|
OR (95% CI)
|
p value
|
OR (95% CI)
|
p value
|
|---|
|
Age group (Ref: 19–54)
|
|
55–64
|
4.07 (1.85–8.98)
|
0.001
| | |
4
|
|
65–74
|
7.85 (3.54–17.43)
|
< 0.001
| | |
8
|
|
≥ 75
|
11.95 (5.51–25.93)
|
< 0.001
| | |
12
|
|
Specific comorbiditya (Ref: Absence)
|
6.76 (3.89–11.75)
|
< 0.001
|
2.73 (1.28–5.84)
|
0.010
|
3
|
|
Dyspnea (Ref: Absence)
|
2.19 (1.32–3.64)
|
0.002
|
2.09 (1.04–4.20)
|
0.038
|
2
|
|
SpO2 at admission (Ref: ≥95%)
|
|
89–94%
|
3.65 (1.92–6.95)
|
< 0.001
|
2.81 (1.23–6.43)
|
0.014
|
3
|
|
≤ 88%
|
11.18 (5.31–23.53)
|
< 0.001
|
8.81 (3.47–22.42)
|
< 0.001
|
9
|
|
Urea (Ref: ≤40 mg/dL)
|
|
> 40 - < 75 mg/dL
|
2.3 (1.20–4.43)
|
0.013
| | | |
|
≥ 75 mg/dL
|
7.85 (3.69–16.71)
|
< 0.001
| | | |
|
Creatinine (Ref: ≤2.5 mg/dL)
|
|
> 2.5 - < 3 mg/dL
|
4.31 (0.87–21.33)
|
0.073
| | | |
|
≥ 3 mg/dL
|
12.14 (4.38–33.64)
|
< 0.001
| | | |
|
HCT (Ref: > 35%)
|
5.16 (2.95–9.02)
|
< 0.001
|
3.07 (1.50–6.28)
|
0.002
|
3
|
|
NLR (Ref: < 2.95)
|
4.78 (2.46–9.27)
|
< 0.001
| | | |
|
CRP (Ref: ≤50 mg/L)
|
|
> 50 - < 100 mg/L
|
4.06 (1.82–9.06)
|
0.001
|
1.5 (0.55–4.11)
|
0.431
|
2
|
|
≥ 100 mg/L
|
12.75 (6.44–25.26)
|
< 0.001
|
5.67 (2.48–12.95)
|
< 0.001
|
6
|
|
AST (Ref: ≤40 IU/L)
|
|
> 40 - < 80 IU/L
|
2.69 (1.39–5.19)
|
0.003
|
1.97 (0.85–4.55)
|
0.113
|
2
|
|
≥ 80 IU/L
|
15.62 (7.13–34.24)
|
< 0.001
|
6.81 (2.45–18.09)
|
< 0.001
|
7
|
|
ALT (Ref: ≤40 IU/L)
|
|
> 40 - < 80 IU/L
|
2.36 (1.19–4.68)
|
0.014
| | | |
|
≥ 80 IU/L
|
4.54 (1.87–10.94)
|
0.001
| | | |
|
Ferritin (Ref: ≤400 ng/mL)
|
|
> 400 - < 1000 ng/mL
|
3.69 (1.73–7.88)
|
0.001
|
1.5 (0.62–3.65)
|
0.368
|
2
|
|
≥ 1000 ng/mL
|
20.78 (9.83–43.93)
|
< 0.001
|
4.72 (2.05–10.91)
|
< 0.001
|
5
|
|
LDH (Ref: ≤400 IU/L)
|
|
> 400 - < 700 IU/L
|
5.19 (2.80–9.64)
|
< 0.001
| | | |
|
≥ 700 IU/L
|
19.44 (7.26–52.02)
|
< 0.001
| | | |
|
Fibrinogen (Ref: ≤ 400 mg/dL)
|
|
> 400 - < 750 mg/dL
|
1.57 (0.87–2.82)
|
0.136
| | | |
|
≥ 750 mg/dL
|
1.97 (0.76–5.13)
|
0.164
| | | |
|
D-dimer (Ref: ≤4 mg/L)
|
|
> 4 - < 7 mg/L
|
5.39 (1.98–14.64)
|
0.001
| | | |
|
≥ 7 mg/L
|
10.12 (4.55–22.52)
|
< 0.001
| | | |
- Ref Reference category, SpO2 Oxygen saturation, HCT Hematocrit, NLR Neutrophil to lymphocyte ratio, CRP C-reactive protein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, LDH Lactate dehydrogenase.
- a Having at least one of the following comorbidities: cancer, heart failure, chronic renal failure
- b Adjusted for age group and sex, except the age group only adjusted for sex
