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Table 2 Odds ratio and 95% confidence interval for the risk of fatal outcome

From: An easy-to-use nomogram for predicting in-hospital mortality risk in COVID-19: a retrospective cohort study in a university hospital

  Adjustedb analysis Multivariable analysis Point
Parameters OR (95% CI) p value OR (95% CI) p value
Age group (Ref: 19–54)
 55–64 4.07 (1.85–8.98) 0.001    4
 65–74 7.85 (3.54–17.43) < 0.001    8
 ≥ 75 11.95 (5.51–25.93) < 0.001    12
Specific comorbiditya (Ref: Absence) 6.76 (3.89–11.75) < 0.001 2.73 (1.28–5.84) 0.010 3
Dyspnea (Ref: Absence) 2.19 (1.32–3.64) 0.002 2.09 (1.04–4.20) 0.038 2
SpO2 at admission (Ref: ≥95%)
 89–94% 3.65 (1.92–6.95) < 0.001 2.81 (1.23–6.43) 0.014 3
 ≤ 88% 11.18 (5.31–23.53) < 0.001 8.81 (3.47–22.42) < 0.001 9
Urea (Ref: ≤40 mg/dL)
 > 40 - < 75 mg/dL 2.3 (1.20–4.43) 0.013    
 ≥ 75 mg/dL 7.85 (3.69–16.71) < 0.001    
Creatinine (Ref: ≤2.5 mg/dL)
 > 2.5 - < 3 mg/dL 4.31 (0.87–21.33) 0.073    
 ≥ 3 mg/dL 12.14 (4.38–33.64) < 0.001    
HCT (Ref: > 35%) 5.16 (2.95–9.02) < 0.001 3.07 (1.50–6.28) 0.002 3
NLR (Ref: < 2.95) 4.78 (2.46–9.27) < 0.001    
CRP (Ref: ≤50 mg/L)
 > 50 - < 100 mg/L 4.06 (1.82–9.06) 0.001 1.5 (0.55–4.11) 0.431 2
 ≥ 100 mg/L 12.75 (6.44–25.26) < 0.001 5.67 (2.48–12.95) < 0.001 6
AST (Ref: ≤40 IU/L)
 > 40 - < 80 IU/L 2.69 (1.39–5.19) 0.003 1.97 (0.85–4.55) 0.113 2
 ≥ 80 IU/L 15.62 (7.13–34.24) < 0.001 6.81 (2.45–18.09) < 0.001 7
ALT (Ref: ≤40 IU/L)
 > 40 - < 80 IU/L 2.36 (1.19–4.68) 0.014    
 ≥ 80 IU/L 4.54 (1.87–10.94) 0.001    
Ferritin (Ref: ≤400 ng/mL)
 > 400 - < 1000 ng/mL 3.69 (1.73–7.88) 0.001 1.5 (0.62–3.65) 0.368 2
 ≥ 1000 ng/mL 20.78 (9.83–43.93) < 0.001 4.72 (2.05–10.91) < 0.001 5
LDH (Ref: ≤400 IU/L)
 > 400 - < 700 IU/L 5.19 (2.80–9.64) < 0.001    
 ≥ 700 IU/L 19.44 (7.26–52.02) < 0.001    
Fibrinogen (Ref: ≤ 400 mg/dL)
 > 400 - < 750 mg/dL 1.57 (0.87–2.82) 0.136    
 ≥ 750 mg/dL 1.97 (0.76–5.13) 0.164    
D-dimer (Ref: ≤4 mg/L)
 > 4 - < 7 mg/L 5.39 (1.98–14.64) 0.001    
 ≥ 7 mg/L 10.12 (4.55–22.52) < 0.001    
  1. Ref Reference category, SpO2 Oxygen saturation, HCT Hematocrit, NLR Neutrophil to lymphocyte ratio, CRP C-reactive protein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, LDH Lactate dehydrogenase.
  2. a Having at least one of the following comorbidities: cancer, heart failure, chronic renal failure
  3. b Adjusted for age group and sex, except the age group only adjusted for sex
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