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Table 2 Odds ratio and 95% confidence interval for the risk of fatal outcome

From: An easy-to-use nomogram for predicting in-hospital mortality risk in COVID-19: a retrospective cohort study in a university hospital

 

Adjustedb analysis

Multivariable analysis

Point

Parameters

OR (95% CI)

p value

OR (95% CI)

p value

Age group (Ref: 19–54)

 55–64

4.07 (1.85–8.98)

0.001

  

4

 65–74

7.85 (3.54–17.43)

< 0.001

  

8

 ≥ 75

11.95 (5.51–25.93)

< 0.001

  

12

Specific comorbiditya (Ref: Absence)

6.76 (3.89–11.75)

< 0.001

2.73 (1.28–5.84)

0.010

3

Dyspnea (Ref: Absence)

2.19 (1.32–3.64)

0.002

2.09 (1.04–4.20)

0.038

2

SpO2 at admission (Ref: ≥95%)

 89–94%

3.65 (1.92–6.95)

< 0.001

2.81 (1.23–6.43)

0.014

3

 ≤ 88%

11.18 (5.31–23.53)

< 0.001

8.81 (3.47–22.42)

< 0.001

9

Urea (Ref: ≤40 mg/dL)

 > 40 - < 75 mg/dL

2.3 (1.20–4.43)

0.013

   

 ≥ 75 mg/dL

7.85 (3.69–16.71)

< 0.001

   

Creatinine (Ref: ≤2.5 mg/dL)

 > 2.5 - < 3 mg/dL

4.31 (0.87–21.33)

0.073

   

 ≥ 3 mg/dL

12.14 (4.38–33.64)

< 0.001

   

HCT (Ref: > 35%)

5.16 (2.95–9.02)

< 0.001

3.07 (1.50–6.28)

0.002

3

NLR (Ref: < 2.95)

4.78 (2.46–9.27)

< 0.001

   

CRP (Ref: ≤50 mg/L)

 > 50 - < 100 mg/L

4.06 (1.82–9.06)

0.001

1.5 (0.55–4.11)

0.431

2

 ≥ 100 mg/L

12.75 (6.44–25.26)

< 0.001

5.67 (2.48–12.95)

< 0.001

6

AST (Ref: ≤40 IU/L)

 > 40 - < 80 IU/L

2.69 (1.39–5.19)

0.003

1.97 (0.85–4.55)

0.113

2

 ≥ 80 IU/L

15.62 (7.13–34.24)

< 0.001

6.81 (2.45–18.09)

< 0.001

7

ALT (Ref: ≤40 IU/L)

 > 40 - < 80 IU/L

2.36 (1.19–4.68)

0.014

   

 ≥ 80 IU/L

4.54 (1.87–10.94)

0.001

   

Ferritin (Ref: ≤400 ng/mL)

 > 400 - < 1000 ng/mL

3.69 (1.73–7.88)

0.001

1.5 (0.62–3.65)

0.368

2

 ≥ 1000 ng/mL

20.78 (9.83–43.93)

< 0.001

4.72 (2.05–10.91)

< 0.001

5

LDH (Ref: ≤400 IU/L)

 > 400 - < 700 IU/L

5.19 (2.80–9.64)

< 0.001

   

 ≥ 700 IU/L

19.44 (7.26–52.02)

< 0.001

   

Fibrinogen (Ref: ≤ 400 mg/dL)

 > 400 - < 750 mg/dL

1.57 (0.87–2.82)

0.136

   

 ≥ 750 mg/dL

1.97 (0.76–5.13)

0.164

   

D-dimer (Ref: ≤4 mg/L)

 > 4 - < 7 mg/L

5.39 (1.98–14.64)

0.001

   

 ≥ 7 mg/L

10.12 (4.55–22.52)

< 0.001

   
  1. Ref Reference category, SpO2 Oxygen saturation, HCT Hematocrit, NLR Neutrophil to lymphocyte ratio, CRP C-reactive protein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, LDH Lactate dehydrogenase.
  2. a Having at least one of the following comorbidities: cancer, heart failure, chronic renal failure
  3. b Adjusted for age group and sex, except the age group only adjusted for sex
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BMC Infectious Diseases

ISSN: 1471-2334

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