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Table 1 The demographic, clinical, and initial laboratory parameters of the patients

From: An easy-to-use nomogram for predicting in-hospital mortality risk in COVID-19: a retrospective cohort study in a university hospital

Parameters Non-survivor
(n = 75)
Survivor
(n = 634)
p-value
Age, mean ± SD 69 ± 14 55 ± 15 < 0.001
Sex (Female), n (%) 31 (41) 295 (47) 0.393ǂ
Age group, n (%)    < 0.001ǂ
 19–54 10 (13) 327 (52)  
 55–64 19 (25) 149 (24)  
 65–74 20 (27) 85 (13)  
 ≥ 75 26 (35) 73 (12)  
Comorbidities, n (%)
 Hypertension 29 (39) 143 (23) 0.002ǂ
 Diabetes Mellitus 19 (25) 73 (12) 0.001ǂ
 Cancer 24 (32) 24 (4) < 0.001ǂ
 Heart failure 11 (15) 21 (3) < 0.001ǂ
 Asthma/COPD 11 (15) 58 (9) 0.127ǂ
 Coronary artery disease 9 (12) 42 (7) 0.088ǂ
 Chronic renal failure 11 (15) 19 (3) < 0.001ǂ
Symptoms, n (%)
 Fever 21 (28) 212 (33) 0.343ǂ
 Cough 16 (21) 280 (44) < 0.001ǂ
 Dyspnea 36 (48) 181 (29) 0.001ǂ
SpO2 at admission, n (%)    < 0.001ǂ
 ≥ 95% 16 (22) 375 (63)  
 89–94% 32 (44) 182 (30)  
 ≤ 88% 25 (34) 41 (7)  
Initial laboratory results, n (%)
HCT    < 0.001ǂ
  > 35% 24 (32) 472 (75)  
  ≤ 35% 50 (68) 160 (25)  
NLR    < 0.001ǂ
  < 2.95 12 (17) 362 (57)  
  ≥ 2.95 60 (83) 272 (43)  
CRP    < 0.001ǂ
  ≤ 50 mg/L 13 (18) 439 (69)  
  > 50 - < 100 mg/L 14 (19) 108 (17)  
  ≥ 100 mg/L 47 (64) 86 (14)  
Urea    < 0.001ǂ
  ≤ 40 mg/dL 26 (35) 493 (78)  
  > 40 - < 75 mg/dL 24 (32) 110 (17)  
  ≥ 75 mg/dL 24 (32) 30 (5)  
Creatinine    < 0.001ǂ
  ≤ 1.5 mg/dL 52 (70) 585 (92)  
  > 1.5 - < 3 mg/dL 10 (14) 40 (6)  
  ≥ 3 mg/dL 12 (16) 8 (1)  
AST    < 0.001ǂ
  ≤ 40 IU/L 37 (49) 530 (84)  
  > 40 - < 80 IU/L 17 (23) 87 (14)  
  ≥ 80 IU/L 21 (28) 17 (3)  
ALT    < 0.001ǂ
  ≤ 40 IU/L 50 (68) 534 (84)  
  > 40 - < 80 IU/L 14 (19) 76 (12)  
  ≥ 80 IU/L 10 (14) 24 (4)  
Ferritin    < 0.001ǂ
  ≤ 400 ng/mL 17 (26) 446 (73)  
  > 400 - < 1000 ng/mL 16 (24) 123 (20)  
  ≥ 1000 ng/mL 33 (50) 45 (7)  
LDH    < 0.001ǂ
  ≤ 400 IU/L 37 (49) 561 (89)  
  > 400 - < 700 IU/L 26 (35) 62 (10)  
  ≥ 700 IU/L 12 (16) 10 (2)  
Fibrinogen    0.030ǂ
  ≤ 400 mg/dL 19 (27) 252 (43)  
  > 400 - < 750 mg/dL 43 (61) 294 (50)  
  ≥ 750 mg/dL 8 (11) 41 (7)  
D-dimer    < 0.001§
  ≤ 4 mg/L 47 (65) 590 (96)  
  > 4 - < 7 mg/L 8 (11) 12 (2)  
  ≥ 7 mg/L 17 (24) 16 (3)  
  1. SD Standard deviation, COPD Chronic obstructive pulmonary disease, SpO2 Oxygen saturation, HCT Hematocrit, NLR Neutrophil to lymphocyte ratio, CRP C-reactive protein, AST Aspartate aminotransferase, ALT Alanine aminotransferase, LDH Lactate dehydrogenase
  2. , Student t test; ǂ, Chi-square test; §, Fisher Exact test