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Table 2 Demographic, clinical and diagnostic characteristics at initial presentation of our study cohort

From: Evaluation of patients with respiratory infections during the first pandemic wave in Germany: characteristics of COVID-19 versus non-COVID-19 patients

Diagnostic features
n (%) if not labelled differently
COVID-19 positivea COVID-19 negativea p-value
Total (n = 72) With pneumonia in CT (n = 61) Total (n = 147) With pneumonia in CT (n = 50) Total With Pneumonia
Age in years (mean ± SEM) 60.0 ± 2.0 63.1 ± 2.0 59.5 ± 1.7 61.7 ± 2.9 0.955 0.903
Sex      0.141 0.534
 Male 49 (68.1) 45 (73.8) 83 (56.5) 34 (68.0)   
 Female 23 (31.9) 16 (26.2) 64 (43.5) 16 (32.0)   
Comorbidities in COVID-19 patients
 Total (≥1 system) 52 (72.2) 46 (75.4)     
  Respiratory 10 (13.9) 32 (52.4)     
  Cardiovascular 35 (48.6) 9 (14.8)     
  Oncological 7 (9.7) 7 (11.5)     
  Neurological 8 (11.1) 7 (11.5)     
  Diabetes 11 (15.3) 10 (16.4)     
  Others 32 (44.4) 28 (45.9)     
Duration of symptoms at presentation in days (mean ± SEM) 7.3 ± 0.7 (n = 52)** 7.3 ± 0.6 (n = 45)** 6.6 ± 0.8 (n = 85)** 4.9 ± 0.8 (n = 29)** 0.010 0.003
Body temperature at presentation in °C (mean ± SEM) 37.7 ± 0.1 (n = 65)** 37.7 ± 0.1 (n = 57)** 37.1 ± 0.1 (n = 140)** 37.1 ± 0.1 (n = 48)** < 0.0001 0.0001
Laboratory values at presentation
 CRP (mg/dl)
Threshold ≤5
6.7 ± 0.8
(n = 72)**
7.5 ± 0.9
(n = 61)**
4.7 ± 0.6
(n = 147)**
8.0 ± 1.2
(n = 50)**
0.003 0.808
 Leukocyte counts (G/l)
4.0–10.4 (w)
3.9–9.8 (m)
7.4 ± 0.5
(n = 72)**
7.6 ± 0.5
(n = 61)**
9.3 ± 0.3
(n = 147)**
10.1 ± 0.6
(n = 50)**
< 0.0001 0.0003
 LDH (U/)
Threshold ≤249
370.0 ± 24.7
(n = 68)**
386.3 ± 27.1
(n = 60)**
303.5 ± 18.6
(n = 135)**
310.4 ± 17.5
(n = 50)**
< 0.0001 0.012
 IL-6 (pg/ml)
Threshold ≤5.9
104.7 ± 36.5
(n = 61)**
113.3 ± 39.6
(n = 56)**
177.5 ± 52.9
(n = 105)**
279.6 ± 118.9
(n = 39)**
0.401 0.297
 D-dimer (μg/ml)
Threshold ≤5
2.4 ± 0.8
(n = 61)**
2.6 ± 0.9
(n = 53)**
3.0 ± 0.5
(n = 102)**
3.9 ± 1.0
(n = 38)**
0.924 0.462
Result of RT-PCR
 Positive 72 (100.0) 61 (100.0)   
  By initial test 69 (95.8) 58 (95.1)   
  Several tests necessary for detection 3 (4.2) 3 (4.9)     
   By second test 1 (1.4) 1 (1.6)   
   By third test 1 (1.4) 1 (1.6)   
   By fourth test 1 (1.4) 1 (1.6)   
Negative 147 (100.0) 50 (100.0)   
Radiological imaging at presentation  
CXR 15 (20.8) 11 (18.0) 36 (24.5) 7 (14.0)   
  Pneumonic features
  Present (score 2) 8 (53.3) 8 (72.7) 6 (16.7) 4 (57.1)   
  Possible (score 1) 3 (20.0) 2 (18.2) 7 (19.4) 3 (42.9)   
  Absent (score 0) 4 (26.7) 1 (9.1) 23 (63.9) 0 (0.0)   
Chest CT 69 (95.8) 61 (100.0) 120 (81.6) 50 (100.0)   
 Pneumonic features
 Unilateral   5 (8.2)   21 (42.0)   < 0.0001
 Bilateral   56 (91.8)   29 (58.0)   < 0.0001
 Affected lung lobes (mean ± SEM)   4.3 ± 0.1   2.6 ± 0.2   < 0.0001
 Presence of GGOs   61 (100.0)   48 (96.0)   0.201
 Presence of Consolidations   38 (62.3)   35 (70.0)   0.427
COVID-19 features
 Typical (score 2) 45 (65.2) 45 (73.8) 1 (0.8) 1 (2.0)   
 Possible (score 1) 12 (17.4) 12 (19.7) 13 (10.8) 13 (26.0)   
 Not typical (score 0) 12 (17.4) 4 (6.6) 106 (88.3) 36 (72.0)   
  1. abased on the result in RT-PCR for SARS-CoV-2
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