Parameter
|
HCV RNA positive
n = 93
|
HCV RNA negative
n = 68
|
P value†
|
---|
Male gender
|
48 (51.6)
|
35 (51.5)
|
0.986
|
Age at RRT onset, years
|
45.8 (8.7–79.5)
|
53.5 (14.1–85.9)
|
0.004
|
Diabetic nephropathy
|
17 (18.3)
|
17 (25.0)
|
0.302
|
Chronic glomerulonephritis
|
31 (33.3)
|
11 (16.2)
|
0.014
|
Hypertensive nephropathy
|
10 (10.8)
|
9 (13.2)
|
0.630
|
RRT duration, years
|
13.4 (0–32.0)
|
7.0 (0.2–33.2)
|
0.0009
|
BMI, kg/m2
|
23.1 (15.2–50.4)
|
23.5 (16.2–37.1)
|
0.471
|
HBsAg positivity
|
5 (5.4)
|
5 (7.4)
|
0.744‡
|
Anti-HBc positivity
|
48 (51.6)
|
32 (47.1)
|
0.568
|
Not generating anti-HBs
|
16 (17.2)
|
17 (25.0)
|
0.226
|
Anti-HBs titre, IU/L
|
199.5 (0–8045)
|
284.0 (0–1100)
|
0.889
|
ALT, IU/L
|
24 (2–195)
|
12.4 (3–63)
|
0.00007
|
AST, IU/L
|
23 (8–152)
|
15 (8–46)
|
0.00001
|
ALP, IU/L
|
110 (15–647.3)
|
87.8 (45–803.8)
|
0.016
|
GGT, IU/L
|
48.5 (7–498)
|
27 (7–692)
|
0.001
|
C-reactive protein, mg/L
|
6.0 (0.2–127)
|
5.4 (0.3–101)
|
0.916
|
Albumin, g/dL
|
3.8 (1.9–4.7)
|
4.0 (2–4.9)
|
0.074
|
- Results are presented as median and range (minimum-maximum) or the number of patients presenting the indicated parameter with the % of the total of tested patients shown in parentheses
- Abbreviations: ALP alkaline phosphatase, ALT alanine aminotransferase, AST aspartate aminotransferase, Anti-HBc antibodies against core antigen of hepatitis B virus, Anti-HCV antibodies against hepatitis C virus, BMI body mass index, GGT gamma-glutamyltransferase, HBsAg surface antigen of hepatitis B virus, HCV RNA ribonucleic acid of hepatitis C virus, HD haemodialysis, RRT renal replacement therapy
- Conversion factors to SI units are as follows: for alanine aminotransferase – 1 IU/L = 0.0167 μkat/L, for albumin – 1 g/dL = 10 g/L, for alkaline phosphatase – 1 IU/L = 0.0167 μkat/L, for aspartate aminotransferase – 1 IU/L = 0.0167 μkat/L, for C-reactive protein – 1 mg/L = 9.524 nmol/L, for gamma-glutamyltransferase – 1 IU/L = 0.0167 μkat/L
- † Chi-squared test for qualitative variables and Mann-Whitney test for quantitative variables
- ‡Fisher’s exact test