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Table 2 Matched multivariable adjusted/unadjusted logistic regression models for hospitalization (sample size = 1067)

From: Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study

 

Multivariable Adjusted

Unadjusted

Estimated OR

OR 95% CI

P value

Estimated OR

OR 95% CI

P value

HCQ, yes/no

0.535

(0.291,0.949)

0.038

0.602

(0.356,0.977)

0.048

Age

1.023

(1.012,1.034)

< 0.001

1.021

(1.014,1.029)

< 0.001

Gender, male/female

1.316

(0.957,1.81)

0.091

1.542

(1.187,2.005)

0.001

Diabetes, yes/no

1.255

(0.829,1.895)

0.281

1.653

(1.187,2.295)

0.003

Hypertension yes/no

0.941

(0.644,1.372)

0.753

1.314

(1.007,1.714)

0.044

COPD/Asthma, yes/no

0.718

(0.453,1.126)

0.154

1.093

(0.753,1.571)

0.633

Cancer, yes/no

1.045

(0.607,1.785)

0.872

1.458

(0.948,2.220)

0.081

Presenting Symptoms, n (%)

 Fever, yes/no

1.265

(0.866,1.85)

0.224

1.886

(1.441,2.478)

< 0.001

 Cough, yes/no

0.853

(0.573,1.264)

0.43

1.670

(1.280,2.187)

< 0.001

 Shortness of Breath, yes/no

6.113

(4.307,8.765)

< 0.001

6.210

(4.683,8.278)

< 0.001

Disease severity, n (%)

 qSOFA Score, 1/0

0.193

(0.139,0.265)

< 0.001

0.178

(0.134,0.236)

< 0.001

  1. Test of model goodness of fit shows a good fit with p-value = 0.094 (g = 13) for the multivariable adjusted logistic regression model