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Table 2 Matched multivariable adjusted/unadjusted logistic regression models for hospitalization (sample size = 1067)

From: Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study

  Multivariable Adjusted Unadjusted
Estimated OR OR 95% CI P value Estimated OR OR 95% CI P value
HCQ, yes/no 0.535 (0.291,0.949) 0.038 0.602 (0.356,0.977) 0.048
Age 1.023 (1.012,1.034) < 0.001 1.021 (1.014,1.029) < 0.001
Gender, male/female 1.316 (0.957,1.81) 0.091 1.542 (1.187,2.005) 0.001
Diabetes, yes/no 1.255 (0.829,1.895) 0.281 1.653 (1.187,2.295) 0.003
Hypertension yes/no 0.941 (0.644,1.372) 0.753 1.314 (1.007,1.714) 0.044
COPD/Asthma, yes/no 0.718 (0.453,1.126) 0.154 1.093 (0.753,1.571) 0.633
Cancer, yes/no 1.045 (0.607,1.785) 0.872 1.458 (0.948,2.220) 0.081
Presenting Symptoms, n (%)
 Fever, yes/no 1.265 (0.866,1.85) 0.224 1.886 (1.441,2.478) < 0.001
 Cough, yes/no 0.853 (0.573,1.264) 0.43 1.670 (1.280,2.187) < 0.001
 Shortness of Breath, yes/no 6.113 (4.307,8.765) < 0.001 6.210 (4.683,8.278) < 0.001
Disease severity, n (%)
 qSOFA Score, 1/0 0.193 (0.139,0.265) < 0.001 0.178 (0.134,0.236) < 0.001
  1. Test of model goodness of fit shows a good fit with p-value = 0.094 (g = 13) for the multivariable adjusted logistic regression model