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Table 3 Microbiological aspects associated with sepsis in patients with cellulitis

From: Factors associated with sepsis development in 606 Spanish adult patients with cellulitis

 All
n = 606
No sepsis
(n = 541)
Sepsis
(n = 65)
P value
Culture of the purulent collection
 Pus culture available
  Yes150 (24.8%)129 (23.8%)21 (32.3%)0.14
  No456 (75.2%)412 (76.2%)44 (67.7%) 
 Results of culture
  Positive118 (78.7%)101 (78.3%)17 (81.0%)0.8
  Negative32 (21.3%)28 (21.7%)4 (19.0%) 
 Positive culture
  Monomicrobial92 (78.0%)78 (77.2%)14 (82.4%)0.7
  Polymicrobial26 (22.0%)23 (22.8%)3 (17.6%) 
 Aerobes (monomicrobial) *
  None32 (21.3%)28 (21.7%)4 (19.0%)0.6
S aureus only45 (30.0%)41 (31.8%)4 (19.0%) 
  Streptococci only18 (12.0%)14 (10.9%)4 (19.0%) 
  Gram-neg bacilli only21 (14.0%)17 (13.2%)4 (19.0%) 
  Others/polymicrobial34 (22.7%)29 (22.5%)5 (23.8%) 
 Aerobes (mono or polymicrobial) *
S aureus56 (37.3%)51 (39.5%)5 (23.8%)0.17
  No S aureus94 (62.7%)78 (60.5%)16 (76.2%) 
  Streptococci24 (16.0%)20 (15.5%)4 (19.0%)0.7
  No streptococci126 (84.0%)109 (84.5%)17 (81.0%) 
  Gram-negative bacilli43 (28.7%)37 (28.7%)6 (28.6%)1
  No Gram-neg bacilli107 (71.3%)92 (71.3%)15 (71.4%) 
 Anaerobes *
  Yes8 (5.3%)6 (4.7%)2 (9.5%)0.3
  No142 (94.7%)123 (95.3%)19 (90.5%) 
Blood culture
 Blood culture available
  Yes252 (41.6%)207 (38.3%)45 (69.2%)< 0.0001
  No354 (58.4%)334 (61.7%)20 (30.8%) 
 Results of culture
  Positive46 (18.3%)35 (16.9%)11 (24.4%)0.2
  Negative206 (81.7%)172 (83.1%)34 (75.6%) 
 Positive culture
  Monomicrobial46 (100%)35 (100%)11 (100%)
  Polymicrobial0 (0.0%)0 (0.0%)0 (0.0%) 
 Aerobes **
  None206 (81.7%)172 (83.1%)34 (75.6%)0.7
S aureus8 (3.2%)7 (3.4%)1 (2.2%) 
  Streptococci18 (7.1%)13 (6.3%)5 (11.1%) 
  Gram-neg bacilli7 (2.8%)5 (2.4%)2 (4.4%) 
  Others13 (5.2%)10 (4.8%)3 (6.7%) 
 Anaerobes
  Yes1 (0.4%)0 (0.0%)1 (2.2%)0.18
  No251 (99.6%)207 (100%)44 (97.8%) 
Pus or blood culture
 Any culture
  Yes333 (55.0%)282 (47.9%)51 (78.5%)0.0001
  No273 (45.0%)259 (47.9%)14 (21.5%) 
 Any microorganism identified
  Yes155 (25.6%)129 (23.8%)26 (40.0%)0.005
  No451 (74.4%)412 (76.2%)39 (60.0%) 
 Specific microorganisms ***
  None178 (53.5%)153 (54.3%)25 (49.0%)0.4
S aureus only50 (15.0%)45 (16.0%)5 (9.8%) 
  Streptococci only33 (9.9%)25 (8.9%)8 (15.7%) 
  Gram-neg bacilli only28 (8.4%)22 (7.8%)6 (11.8%) 
  Others/polymicrobial44 (13.2%)37 (13.1%)7 (13.7%) 
 Aerobes (mono or polymicrobial) ***
S aureus61 (18.3%)55 (19.5%)6 (11.8%)0.19
  No S aureus272 (81.7%)227 (80.5%)45 (88.2%) 
  Streptococci40 (12.0%)31 (11.0%)9 (17.6%)0.18
  No streptococci293 (88.0%)251 (89.0%)42 (82.4%) 
  Gram-negative bacilli50 (15.0%)42 (14.9%)8 (15.7%)0.9
  No Gram-neg bacilli283 (85.0%)240 (85.1%)43 (84.3%) 
 Causative microorganisms identified
  Yes143 (23.6%)120 (22.2%)23 (35.4%)0.006
  No453 (74.8%)414 (76.5%)39 (60.0%) 
  Doubtful10 (1.7%)7 (1.3%)3 (4.6%) 
  1. * Respect to all patients with pus (*), blood (**) or any (***) culture