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Table 2 Associations between different factors and US rates of mortality with sepsis in a multivariable model

From: The relation between prescribing of different antibiotics and rates of mortality with sepsis in US adults

 Aged 18-49yAged 50-64yAged 65-74yAged 75-84yAged 85 + y
Fluoroquinolones (prescription per 1000 residents/y)0.01 (− 0.04,0.07)0.15 (− 0.15,0.45)0.26 (− 0.4,0.92)− 0.16 (− 1.77,1.45)− 0.61 (− 4.52,3.3)
Penicillins (prescription per 1000 residents/y)− 0.03 (− 0.07,0)0.08 (− 0.1,0.25)0.11 (− 0.28,0.5)0.95 (0.02,1.88)2.97 (0.72,5.22)
Cephalosporins (prescription per 1000 residents/y)0.05 (0.02,0.09)0.07 (− 0.11,0.25)0.13 (− 0.28,0.55)−0.06 (− 1.04,0.93)−0.76 (− 3.09,1.58)
Macrolides (prescription per 1000 residents/y)0.02 (− 0.02,0.06)0.06 (− 0.15,0.26)0.21 (− 0.26,0.69)0.45 (− 0.69,1.58)0.71 (−2.03,3.45)
Median household income ($1000)−0.06 (− 0.13,0.01)−0.17 (− 0.55,0.2)−0.09 (− 0.9,0.73)0.54 (− 1.4,2.49)1.95 (− 2.7,6.59)
Average minimal daily temperature (°F)− 0.04 (− 0.11,0.03)0.16 (− 0.19,0.51)0.33 (− 0.44,1.1)0.6 (− 1.26,2.46)4.07 (− 0.55,8.7)
Percent African Americans0.03 (− 0.05,0.11)0.28 (−0.06,0.63)1.25 (0.41,2.1)2.68 (0.76,4.6)3.02 (− 1.63,7.66)
Percent lacking health insurance0.05 (−0.1,0.2)0.95 (0.01,1.89)NDNDND
  1. Regression coefficients for the different covariates in the model given by eq. 1 for different age groups. The coefficients for the different antibiotic classes estimate the change in the annual rates of mortality with sepsis (per 10,000 individuals in a given age group) when the annual rate of outpatient prescribing of oral antibiotics in the corresponding class (per 1000 residents) increases by 1. ND = not done because persons aged > 64 years old are eligible for Medicare