Table 1 List of unique P. vivax proteins detected in plasma (A) and parasite isolates (B) by mass spectrometry

S. No

Gene ID

Protein description

Number of samples

Number of peptides

 1

PVX_081832

Plasmodium exported protein

4

1, 1, 1, 1

 2

PVX_083555

hypothetical protein

3

1, 4, 2

 3

PVX_094303

Pvstp1

2

4, 4

 4

PVX_090970

hypothetical protein

2

2, 2

 5

PVX_003555

Plasmodium exported protein

2

2, 1

 6

PVX_121935

Plasmodium exported protein

2

2, 1

 7

PVX_001650

Pv-fam-d protein

2

1, 1

 8

PVX_003545

Plasmodium exported protein

2

1, 1

S. No

Gene ID

Protein description

Number of isolates

Number of peptides

 1

PVX_094303

Pvstp1, putative

14

6,5,5,2,4,14,3,4,5,12,26,2,2,2

 2

PVX_003555

Plasmodium exported protein, unknown function

13

22,15,5,10,4,18,3,4,17,21,2,5,1

 3

PVX_003545

Plasmodium exported protein, unknown function

12

3,2,3,1,3,4,2,2,2,7,9,1

 4

PVX_092990

tryptophan-rich antigen (Pv-fam-a)

10

15,6,2,5,11,1,1,6,11,1

 5

PVX_092995

tryptophan-rich antigen (Pv-fam-a)

10

1,11,2,8,5,2,2,5,15,2

 6

PVX_096975

VIR protein

9

1,6,1,4,2,1,3,6,1

 7

PVX_112670

unspecified product

9

4,5,2,2,2,2,1,1,4

 8

PVX_090265

tryptophan-rich antigen (Pv-fam-a)

9

2,14,3,5,4,3,4,21,3

 19

PVX_001685

Phist protein (Pf-fam-b)

8

7,2,3,1,4,3,7,1

 10

PVX_094295

Pv-fam-h protein

8

3,1,1,1,2,4,1,1

 11

PVX_096995

tryptophan-rich antigen (Pv-fam-a)

8

12,4,4,6,3,13,1,1

 12

PVX_118695

Pv-fam-d protein

8

10,6,1,1,10,3,17,1

 13

PVX_121935

Plasmodium exported protein, unknown function

8

3,4,4,2,4,2,10,3

 14

PVX_083555

hypothetical protein

7

2,1,2,1,5,11,2

 15

PVX_090275

tryptophan-rich antigen (Pv-fam-a)

7

1,1,4,4,1,2,16

 16

PVX_096985

variable surface protein Vir, putative

7

3,4,1,1,7,1,1

 17

PVX_101515

tryptophan-rich antigen (Pv-fam-a)

7

6,1,2,3,4,12,1

 18

PVX_112110

unspecified product

7

1,5,4,7,3,1,1

 19

PVX_115460

Plasmodium exported protein, unknown function

7

2,1,1,1,2,2,3