Table 4 Break points of different antifungal drugs against Candida Isolates
Species | Antifungal drug | Break points μg/ml | ||
|---|---|---|---|---|
| Â | Susceptible | Intermediate | Resistant | |
|  | Fluconazole | 1–4 | 16–32 | 0 |
|  | Voriconazole | 0.12–0.5 | – | – |
C. albicans | Caspofungin | 0.12–1 | – | 4 |
Micafungin | 0.06–0.5 | – | 4 | |
Flucytosine | 1 | 8 | 64 | |
Fluconazole | 0 | – | 16 | |
Voriconazole | 0.12–0.25 | – | – | |
C. krursei | Caspofungin | 0.12–0.5 | – | – |
Micafungin | 0.06–0.25 | – | – | |
Flucytosine | 1 | 16 | 64 | |
Fluconazole | * | * | * | |
Voriconazole | * | * | * | |
C. famata | Caspofungin | * | * | * |
Micafungin | * | * | * | |
Flucytosine | * | * | * | |
Fluconazole | 1–8 | 32 | 64 | |
Voriconazole | 0.12 | – | – | |
C. rugosa | Caspofungin | 0.25 | – | 4 |
Micafungin | 0.06–0.12 |  | 4 | |
Flucytosine | 1 | 16 | – | |
Fluconazole | 1–2 |  |  | |
Voriconazole | 0.12–0.5 | – | – | |
C. lusitaniae | Caspofungin | 0.25–1 | – | – |
Micafungin | 0.06–1 | – | – | |
Flucytosine | 1 | – | – | |
Fluconazole | 1–8 | 32 | – | |
Voriconazole | 0.12 | – | – | |
C. dubliniensis | Caspofungin | 0.12–0.25 | – | – |
Micafungin | 0.06–0.25 | – | – | |
Flucytosine | 4 | 8 | – | |
Fluconazole | 1–8 | 16 | 64 | |
Voriconazole | 0.12 | – | – | |
C.lipolytica | Caspofungin | 0.12–0.25 | – | ≥ 4 |
Micafungin | 0.06–0.25 | – | ≥ 4 | |
Flucytosine | 8 | 16 | – | |
Fluconazole | 1 | – | – | |
Voriconazole | 0.12 | – | – | |
C. parapsilosis | Caspofungin | 0.12–1 | – | – |
Micafungin | 0.25–2 | – | – | |
Flucytosine | 1 | – | – | |
Fluconazole | 1–8 | 16 | 64 | |
Voriconazole | 0.12 | – | 32 | |
C. ciferrii | Caspofungin | * | * | * |
Micafungin | * | * | * | |
Flucytosine | 2 | 8 | – | |
Fluconazole | 1 | – | – | |
Voriconazole | 0.12 | – | – | |
C. kefyr | Caspofungin | .025–0.5 | – | – |
Micafungin | 0.06.0.12 | – | – | |
Flucytosine | 1 | – | – | |
Fluconazole | 1–4 | 16 | – | |
Voriconazole | 0.12 | – | – | |
C. guilliermondii | Caspofungin | 0.25–1 | – | – |
Micafungin | 0.06–0.5 | – | – | |
Flucytosine | 1 | – | – | |
Fluconazole | 2 | – | 64 | |
Voriconazole | 0.12–0.5 | – | – | |
C. pelliculosa | Caspofungin | 0.25 | – | – |
Micafungin | 0.06–0.12 | – | – | |
Flucytosine | 1–4 | – | – | |
Fluconazole | 4 | – | – | |
Voriconazole | 0.12 | – | – | |
C. glabrata | Caspofungin | 0.25 | – | – |
Micafungin | 0.06 | – | – | |
Flucytosine | 1 | – | – | |
Fluconazole | 1 | – | – | |
Voriconazole | 0.12 | – | – | |
C. intermedia | Caspofungin | 0.25 | – | – |
Micafungin | 0.12 | – | – | |
Flucytosine | 1 | – | – | |
Fluconazole | 2 | – | – | |
Voriconazole | 0.12 | – | – | |
C. utilis | Caspofungin | 0.25 | – | – |
Micafungin | 0.12 | – | – | |
Flucytosine | 1 | – | – | |