From: Multiplex bacterial polymerase chain reaction in a cohort of patients with pleural effusion
No Empyema | Empyema | p-value | |
---|---|---|---|
Age, y | 70.4 ± 15.4 | 65.0 ± 15.2 | 0.012 |
Length of stay, days | 13 (4.0;22.0) | 25.0 (15.0;35.5) | < 0.001 |
unadjusted Charlson score | 4.9 ± 2.6 | 4.7 ± 3.1 | 0.572 |
ASA score | 3.1 ± 0.46 | 3.0 ± 0.4 | 0.668 |
Smoking status | 0.006 | ||
Current smoker | 25 (17) | 23 (38) | |
Non-smoker | 49 (34) | 16 (27) | |
Blood parameters | |||
Leucocytes (*109/l) | 9.2 ± 7.4 | 13.3 ± 7.1 | < 0.001 |
Neutrophils (*109/l) | 6.2 ± 3.5 | 11.3 ± 7.1 | < 0.001 |
C-reactive protein (mg/l) | 81.3 ± 83.4 | 203.7 ± 116.6 | < 0.001 |
Lactate dehydrogenase (U/l) | 315.8 ± 229.4 | 222.8 ± 132.6 | < 0.001 |
Pleural fluid parameters | |||
Protein (g/l) | 33.6 ± 11.3 | 36.1 ± 12.2 | 0.074 |
Glucose (mmol/l) | 6.1 ± 2.7 | 4.3 ± 3.2 | < 0.001 |
pH | 7.4 ± 0.11 | 7.1 ± 0.3 | < 0.001 |
LDH (U/l) | 439.5 ± 637.5 | 3339.3 ± 7558.9 | < 0.001 |
Antibiotic duration (days) | |||
Before sampling | 0 (0;6) | 4.0 (1.0;9.0) | < 0.001 |
After sampling | 5.0 (0;10) | 26.0 (15.5;37.5) | < 0.001 |
Total antibiotic treatment | 7.0 (0;15) | 31.0 (20;44) | < 0.001 |
Patient outcome | |||
30-day mortality | 12 (9) | 7 (12) | 0.598 |