Skip to main content

Table 2 Unconditional logistic multiple regression model of risk and protection factors for tuberculosis

From: Clinical and genetic markers associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes

FeaturesLevelAll the groupsG1 + G3 vs. G2 + G4HIV-1 positive individualsG1 vs. G2
With TB
(G1 + G3)
N = 112
Without TB
(G2 + G4)
N = 50
aORa95%CIP-valuebWith TB (G1)
N = 88
Without TB (G2)
N = 24
aOR95%CIP-value
GenderMale86 (76.79)27 (54)Ref70 (79.55)16 (66.67)Ref
Female26 (23.21)23 (46)0.330.13–0.80.01418 (20.45)8 (33.33)0.490.17–1.430.192
HLA-B*08not carriers105 (93.75)41 (82)Ref82 (93.18)21 (87.5)Ref
carriers7 (6.25)9 (18)0.230.06–0890.0336 (6.82)3 (12.5)0.530.1–2.770.450
KIR2DL3carriers105 (93.75)44 (88)Ref84 (95.45)19 (79.17)Ref
not carriers7 (6.25)6 (12)0.520.14–1.890.3194 (4.55)5 (20.83)0.180.04–0.740.034
KIR2DS2not carriers50 (44.64)29 (58)Ref42 (47.73)14 (58.33)Ref
carriers62 (55.36)21 (42)2.391.03–5.540.04346 (52.27)10 (41.67)1.740.66–4.640.265
HLA-C*07ccarriers37 (33.64)c20 (40)0.750.32–1.710.48928 (32.56)c12 (50)0.320.11–0.940.038
not carriers73 (66.36)c30 (60)Ref58 (67.44)c12 (50)Ref
  1. aOdds ratios were adjusted by gender, skin color, education, HIV status, CD4 count, and CD4/CD8 ratio when appropriate. bP-values were calculated using the unconditional logistic regression model. Differences were considered significant with a value of * P < 0.05. Significant P-values are labeled in bold. cThe HLA-C determination was not possible for two individuals from G1. So, when considering this variable, N (G1) = 86 and N (G1 + G3) = 110
  2. N number of individuals in each group, aOR adjusted odds ratio, 95% CI 95% confidence interval, REF Reference, G1 group 1, G2 group 2, G3 group 3. G4 group 4