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Table 1 Sociodemographic, clinical, and laboratory data for individuals included in the study categorized according to the presence (Group 1 + Group 3) or absence (Group 2 + Group 4) of TB

From: Clinical and genetic markers associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes

Features Overall
N = 162
With TB
(G1 + G3)
N = 112
Without TB
(G2 + G4)
N = 50
P-valuea
Gender; n (%)
 Female 49 (30.2) 26 (23.21) 23 (46) 0.005
 Male 113 (69.8) 86 (76.79) 27 (54)  
Skin Colorb; n (%)
 Black 32 (19.8) 25 (22.32) 7 (14) 0.379
 Brown 64 (39.5) 41 (36.61) 23 (46)  
 White 66 (40.7) 46 (41.07) 20 (40)  
Educationc; n (%)
 Bachelor 13 (8) 6 (5.36) 7 (14) <0.001
 Upper-secondary 49 (30.2) 27 (24.11) 22 (44)  
 Lower-secondary 67 (41.4) 46 (41.07) 21 (42)  
 Primary 26 (16) 26 (23.21) 0 (0)  
 Unknown 7 (4.3) 7 (6.25) 0 (0)  
HIV status; n (%)
 Negative 50 (30.9) 24 (21.43) 26 (52) 0.0002
 Positive 112 (69.1) 88 (78.57) 24 (48)  
CD4 count (cell/μL) (IQR) 153 (654.25) 130.5 (116.51) 674 (1348) 0.003
 (≤50); n (%) 40 (25.3) 28 (25) 12 (24) 0.846
 (>50); n (%) 118 (74.7) 80 (71.43) 38 (76)  
CD8 (IQR) 588 (562) 591 (527.7) 564 (1.128)  
 (≤500); n (%) 65 (42.5) 44 (39.28) 21 (42) 1
 (>500); n (%) 88 (57.5) 59 (52.68) 29 (58)  
CD4/CD8 (IQR) 0.29 (0.96) 0.2 (0.18) 0.69 (1.38) 0.004
 (≤1); n (%) 111 (72.5) 85 (75.89) 26 (52) 0.0002
 (>1); n (%) 42 (27.5) 18 (16.07) 24 (48)  
  1. N number of individuals in each group, TB tuberculosis, IQR interquartile range, VL viral load, G1 group 1, G2 group 2, G3 group 3, G4 group 4
  2. aP-values were calculated using Fisher’s exact test. Differences were considered significant with a value of * P < 0.05. Significant P-values are labeled in bold. bSkin color categorization followed the classificatory system employed by the Brazilian Institute of Geography and Statistics (IBGE) [59]. cClassification, according to the International Standard Classification of Education (ISCED) maintained by the United Nations Educational, Scientific and Cultural Organization (UNESCO)