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Table 1 Sociodemographic, clinical, and laboratory data for individuals included in the study categorized according to the presence (Group 1 + Group 3) or absence (Group 2 + Group 4) of TB

From: Clinical and genetic markers associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes

Features

Overall

N = 162

With TB

(G1 + G3)

N = 112

Without TB

(G2 + G4)

N = 50

P-valuea

Gender; n (%)

 Female

49 (30.2)

26 (23.21)

23 (46)

0.005

 Male

113 (69.8)

86 (76.79)

27 (54)

 

Skin Colorb; n (%)

 Black

32 (19.8)

25 (22.32)

7 (14)

0.379

 Brown

64 (39.5)

41 (36.61)

23 (46)

 

 White

66 (40.7)

46 (41.07)

20 (40)

 

Educationc; n (%)

 Bachelor

13 (8)

6 (5.36)

7 (14)

<0.001

 Upper-secondary

49 (30.2)

27 (24.11)

22 (44)

 

 Lower-secondary

67 (41.4)

46 (41.07)

21 (42)

 

 Primary

26 (16)

26 (23.21)

0 (0)

 

 Unknown

7 (4.3)

7 (6.25)

0 (0)

 

HIV status; n (%)

 Negative

50 (30.9)

24 (21.43)

26 (52)

0.0002

 Positive

112 (69.1)

88 (78.57)

24 (48)

 

CD4 count (cell/μL) (IQR)

153 (654.25)

130.5 (116.51)

674 (1348)

0.003

 (≤50); n (%)

40 (25.3)

28 (25)

12 (24)

0.846

 (>50); n (%)

118 (74.7)

80 (71.43)

38 (76)

 

CD8 (IQR)

588 (562)

591 (527.7)

564 (1.128)

 

 (≤500); n (%)

65 (42.5)

44 (39.28)

21 (42)

1

 (>500); n (%)

88 (57.5)

59 (52.68)

29 (58)

 

CD4/CD8 (IQR)

0.29 (0.96)

0.2 (0.18)

0.69 (1.38)

0.004

 (≤1); n (%)

111 (72.5)

85 (75.89)

26 (52)

0.0002

 (>1); n (%)

42 (27.5)

18 (16.07)

24 (48)

 
  1. N number of individuals in each group, TB tuberculosis, IQR interquartile range, VL viral load, G1 group 1, G2 group 2, G3 group 3, G4 group 4
  2. aP-values were calculated using Fisher’s exact test. Differences were considered significant with a value of * P < 0.05. Significant P-values are labeled in bold. bSkin color categorization followed the classificatory system employed by the Brazilian Institute of Geography and Statistics (IBGE) [59]. cClassification, according to the International Standard Classification of Education (ISCED) maintained by the United Nations Educational, Scientific and Cultural Organization (UNESCO)