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Table 6 Univariate and multivariate logistic regression analysis of risk factors for postoperative infection in children with congenital heart disease

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter   Univariate analysis Multivariate analysis
OR (95% CI) P-value OR (95% CI) P value
Age (days) Unit = 30 0.998 (0.993,1.003) 0.43   
Gender Female 1.000    
Male 0.963 (0.756,1.227) 0.761   
Preterm birth No 1.000    
Yes 0.989 (0.237,4.124) 0.988   
History of cardiac surgery No 1.000    
Yes 2.741 (2.092,3.59) < 0.001   
STS risk grade Unit = 1 2.07 (1.843,2.326) < 0.001 1.38 (1.167,1.633) < 0.001
Delayed sternal closure No 1.000    
Yes 9.268 (2.774,30.965) < 0.001   
BMI 5th–95th percentile 1.000    
< 5th percentile 2.209 (1.671,2.922) < 0.001 1.934 (1.377,2.715) < 0.001
> 95th percentile 0.618 (0.287,1.331) 0.219 0.864 (0.37,2.017) 0.736
CPB time Unit = 1 1.019 (1.016,1.021) < 0.001 1.018 (1.015,1.022) < 0.001
Aortic clamping time Unit = 1 1.027 (1.024,1.031) < 0.001   
Lymphocyte count Normal 1.000    
< cut off value 4.097 (1.736,9.668) 0.001   
>cut off value 0.735 (0.571,0.947) 0.017   
Lymphocytes /WBC Normal 1.000    
< cut off value 3.243 (1.607,6.543) 0.001 3.818 (1.529,9.533) 0.004
>cut off value 0.714 (0.534,0.956) 0.024 0.959 (0.658,1.399) 0.829
Neutrophil count Normal 1.000    
< cut off value 0.956 (0.61,1.497) 0.843   
>cut off value 1.889 (1.296,2.754) 0.001   
Neutrophil /WBC Normal 1.000    
< cut off value 0.853 (0.634,1.148) 0.295   
>cut off value 2.426 (1.223,4.814) 0.011   
ALT Normal 1.000    
< cut off value 1.338 (0.824,2.171) 0.239   
>cut off value 3.696 (1.974,6.921) < 0.001   
AST Normal 1.000    
>cut off value 1.911 (1.454,2.512) < 0.001 1.546 (1.119,2.136) 0.008
ALP Normal 1.000    
>cut off value 0.596 (0.081,4.369) 0.61   
Serum creatinine Normal 1.000    
< cut off value 0 (0,.) 0.98   
>cut off value 10.22 (0.923,113.101) 0.058   
  1. Note: CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell