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Table 6 Univariate and multivariate logistic regression analysis of risk factors for postoperative infection in children with congenital heart disease

From: Risk factors of nosocomial infection after cardiac surgery in children with congenital heart disease

Parameter Univariate analysisMultivariate analysis
OR (95% CI)P-valueOR (95% CI)P value
Age (days)Unit = 300.998 (0.993,1.003)0.43  
GenderFemale1.000   
Male0.963 (0.756,1.227)0.761  
Preterm birthNo1.000   
Yes0.989 (0.237,4.124)0.988  
History of cardiac surgeryNo1.000   
Yes2.741 (2.092,3.59)< 0.001  
STS risk gradeUnit = 12.07 (1.843,2.326)< 0.0011.38 (1.167,1.633)< 0.001
Delayed sternal closureNo1.000   
Yes9.268 (2.774,30.965)< 0.001  
BMI5th–95th percentile1.000   
< 5th percentile2.209 (1.671,2.922)< 0.0011.934 (1.377,2.715)< 0.001
> 95th percentile0.618 (0.287,1.331)0.2190.864 (0.37,2.017)0.736
CPB timeUnit = 11.019 (1.016,1.021)< 0.0011.018 (1.015,1.022)< 0.001
Aortic clamping timeUnit = 11.027 (1.024,1.031)< 0.001  
Lymphocyte countNormal1.000   
< cut off value4.097 (1.736,9.668)0.001  
>cut off value0.735 (0.571,0.947)0.017  
Lymphocytes /WBCNormal1.000   
< cut off value3.243 (1.607,6.543)0.0013.818 (1.529,9.533)0.004
>cut off value0.714 (0.534,0.956)0.0240.959 (0.658,1.399)0.829
Neutrophil countNormal1.000   
< cut off value0.956 (0.61,1.497)0.843  
>cut off value1.889 (1.296,2.754)0.001  
Neutrophil /WBCNormal1.000   
< cut off value0.853 (0.634,1.148)0.295  
>cut off value2.426 (1.223,4.814)0.011  
ALTNormal1.000   
< cut off value1.338 (0.824,2.171)0.239  
>cut off value3.696 (1.974,6.921)< 0.001  
ASTNormal1.000   
>cut off value1.911 (1.454,2.512)< 0.0011.546 (1.119,2.136)0.008
ALPNormal1.000   
>cut off value0.596 (0.081,4.369)0.61  
Serum creatinineNormal1.000   
< cut off value0 (0,.)0.98  
>cut off value10.22 (0.923,113.101)0.058  
  1. Note: CPB cardiopulmonary bypass, BMI body mass index, STS risk grade: Society of Thoracic Surgeons risk grade, ALT alanine transaminase, AST aspartate aminotransferase, ALP alkaline phosphatase, WBC white blood cell