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Table 1 Demographics of emergency department adult patients with suspected bacterial infection

From: Clinical physiological parameters for the prediction of gram-negative bacterial infection in the emergency department

Characteristics

Total patients

(n = 797)

GNB

(n = 278)

Non-GNBa (n = 519)

p-value

Age (mean ± SD)

71.8 ± 17.2

77.0 ± 1.2

69.0 ± 17.5

<  0.01

Male (%)

51.3%

47.5%

53.4%

0.11

Vital signs (mean ± SD)

 Glasgow coma scale

11.5 ± 4.0

10.9 ± 3.8

11.9 ± 4.0

<  0.01

 SBP (mmHg)

96.0 ± 37.3

98.0 ± 35.0

94.9 ± 38.5

0.26

 Heart rate (n/min)

101.7 ± 28.1

105.0 ± 25.2

100.0 ± 29.5

0.02

 Respiratory rate (n/min)

20.8 ± 6.8

21.9 ± 6.6

20.3 ± 6.9

<  0.01

 Body temperature (°C)

37.3 ± 3.6

37.7 ± 1.5

37.0 ± 4.3

0.01

Laboratory data (median, IQR)

 WBC (103/mm3)

11.6 (8.1–16.6)

12.3 (8.8–17.1)

11.4 (7.9–16.4)

0.13

 CRP (mg/dL)

6.6 (2.0–14.8)

7.9 (3.1–17.4)

5.5 (1.3–12.9)

<  0.01

Infection sites (%)

 Pneumonia

26.3%

37.1%

20.6%

<  0.01

 Urinary tract infection

22.1%

55.8%

4.0%

<  0.01

 Intra-abdominal infection

11.4%

17.3%

8.3%

<  0.01

 Soft tissue infection

3.1%

3.2%

3.1%

0.90

 Infectious endocarditis

0.8%

1.4%

0.4%

0.10

 CNS infection

0.1%

0.4%

0%

0.17

 HIV infection

0.4%

0.0%

0.6%

0.20

 Bacteremia

14.3%

36.7%

23.3%

<  0.01

Medical history (%)

 Diabetes

13.2%

11.9%

13.9%

0.43

 Malignancy

18.1%

16.5%

18.9%

0.41

 Chronic kidney disease

12.5%

6.1%

12.0%

<  0.01

 Uremia under hemodialysis

2.9%

0.7%

4.9%

<  0.01

 COPD

1.6%

2.2%

1.3%

0.39

 Liver cirrhosis

4.9%

3.6%

5.6%

0.21

 Autoimmune disease

2.0%

2.2%

1.9%

0.82

 qSOFA ≥2 (%)

42.7%

56.6%

46.4%

<  0.01

 SIRS ≥3 (%)

29.7%

39.6%

24.5%

<  0.01

 Mortality (%)

26.7%

27.7%

24.8%

0.37

  1. GNB gram-negative bacteria, SD standard deviation, SBP systolic blood pressure, IQR interquartile range, WBC white blood cell, CRP C-reactive protein, CNS central nervous system, HIV Human immunodeficiency virus, COPD chronic obstructive pulmonary disease, qSOFA quick sepsis related organ failure assessment, SIRS systemic inflammatory response syndrome
  2. aIncluding culture negative patients