Characteristics | Total patients (n = 797) | GNB (n = 278) | Non-GNBa (n = 519) | p-value |
---|---|---|---|---|
Age (mean ± SD) | 71.8 ± 17.2 | 77.0 ± 1.2 | 69.0 ± 17.5 | < 0.01 |
Male (%) | 51.3% | 47.5% | 53.4% | 0.11 |
Vital signs (mean ± SD) | ||||
Glasgow coma scale | 11.5 ± 4.0 | 10.9 ± 3.8 | 11.9 ± 4.0 | < 0.01 |
SBP (mmHg) | 96.0 ± 37.3 | 98.0 ± 35.0 | 94.9 ± 38.5 | 0.26 |
Heart rate (n/min) | 101.7 ± 28.1 | 105.0 ± 25.2 | 100.0 ± 29.5 | 0.02 |
Respiratory rate (n/min) | 20.8 ± 6.8 | 21.9 ± 6.6 | 20.3 ± 6.9 | < 0.01 |
Body temperature (°C) | 37.3 ± 3.6 | 37.7 ± 1.5 | 37.0 ± 4.3 | 0.01 |
Laboratory data (median, IQR) | ||||
WBC (103/mm3) | 11.6 (8.1–16.6) | 12.3 (8.8–17.1) | 11.4 (7.9–16.4) | 0.13 |
CRP (mg/dL) | 6.6 (2.0–14.8) | 7.9 (3.1–17.4) | 5.5 (1.3–12.9) | < 0.01 |
Infection sites (%) | ||||
Pneumonia | 26.3% | 37.1% | 20.6% | < 0.01 |
Urinary tract infection | 22.1% | 55.8% | 4.0% | < 0.01 |
Intra-abdominal infection | 11.4% | 17.3% | 8.3% | < 0.01 |
Soft tissue infection | 3.1% | 3.2% | 3.1% | 0.90 |
Infectious endocarditis | 0.8% | 1.4% | 0.4% | 0.10 |
CNS infection | 0.1% | 0.4% | 0% | 0.17 |
HIV infection | 0.4% | 0.0% | 0.6% | 0.20 |
Bacteremia | 14.3% | 36.7% | 23.3% | < 0.01 |
Medical history (%) | ||||
Diabetes | 13.2% | 11.9% | 13.9% | 0.43 |
Malignancy | 18.1% | 16.5% | 18.9% | 0.41 |
Chronic kidney disease | 12.5% | 6.1% | 12.0% | < 0.01 |
Uremia under hemodialysis | 2.9% | 0.7% | 4.9% | < 0.01 |
COPD | 1.6% | 2.2% | 1.3% | 0.39 |
Liver cirrhosis | 4.9% | 3.6% | 5.6% | 0.21 |
Autoimmune disease | 2.0% | 2.2% | 1.9% | 0.82 |
qSOFA ≥2 (%) | 42.7% | 56.6% | 46.4% | < 0.01 |
SIRS ≥3 (%) | 29.7% | 39.6% | 24.5% | < 0.01 |
Mortality (%) | 26.7% | 27.7% | 24.8% | 0.37 |