Differences in the clinical characteristics and outcomes of COVID-19 patients in the epicenter and peripheral areas of the pandemic from China: a retrospective, large-sample, comparative analysis

Table 3 Risk of adverse outcomes in Wuhan cohort in reference to the Sichuan cohort

Outcomes	Unadjusted			Adjusted ^a
Outcomes	OR	95%CI	P	OR	95%CI	P
Death	14.286	4.444–45.455	< 0.001	7.643	2.311–25.274	0.001
ICU admission	2.347	1.531–3.597	< 0.001	1.659	1.047–2.627	0.031
Non-invasive mechanical ventilation	1.044	0.635–1.718	0.865	0.651	0.376–1.127	0.125
Invasive mechanical ventilation	0.835	0.327–2.132	0.705	0.381	0.138–1.054	0.063
Tracheotomy	0.668	0.166–2.681-	0.569	0.225	0.050–1.015	0.052
Time from illness onset hospitalization (> 5 days)	6.849	5.208–9.009	< 0.001	6.289	4.695–8.403	< 0.001
Hospital stay (> 17 days)	0.481	0.380–0.609	< 0.001	0.411	0.316–0.533	< 0.001
Time from illness onset to ICU admission (> 7 days)	6.364	1.836–22.061	0.027	8.030	1.740–37.057	< 0.001
Time from illness onset to discharge (> 23 days)	1.180	0.935–1.489	0.163	0.995	0.772–1.281	0.968
Time from illness onset to death (> 10 days)	4.706	0.399–55.447	0.218	4.731	0.314–71.265	0.261
Time from hospitalization to ICU admission (> 4 days)	0.857	0.243–3.024	0.811	0.665	0.122–3.620	0.637
Time from hospital admission to death (> 10 days)	0.426	0.035–5.161	0.502	0.155	0.007–3.694	0.249
Duration of viral shedding (> 13 days)	1.881	1.363–2.597	< 0.001	1.640	1.153–2.333	0.006

ISSN: 1471-2334