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Table 2 Treatments and outcomes of the patients in the Sichuan and Wuhan cohorts

From: Differences in the clinical characteristics and outcomes of COVID-19 patients in the epicenter and peripheral areas of the pandemic from China: a retrospective, large-sample, comparative analysis

Variable

Total

Sichuan cohort

Wuhan cohort

χ2/Z

P value

n

1184

474

710

  

Treatments, n (%)

 Antiviral treatment

1110 (93.8)

448 (94.7)

662 (93.2)

1.067

0.302

 Antibiotics

698 (59.0)

204 (43.0)

494 (69.6)

82.734

< 0.001

 Antifungal treatment

35 (3.0)

15 (3.2)

20 (2.8)

0.120

0.729

 Corticosteroids

272 (23.0)

63 (13.3)

209 (29.4)

41.872

< 0.001

 Intravenous immunoglobin

9 (0.8)

3 (0.6)

6 (0.8)

0.170

0.680

 Oxygen therapy

791 (66.9)

273 (57.7)

518 (731)

30.175

< 0.001

 Prone-position ventilation

30 (2.5)

22 (4.6)

8 (1.1)

14.217

< 0.001

 Tracheotomy

8 (0.7)

4 (0.8)

4 (0.6)

 

0.720*

 ECMO

3 (0.3)

1 (0.2)

2 (0.3)

 

1.000*

 Renal replacement

9 (0.8)

5 (1.1)

4 (0.6)

 

0.497*

 Blood transfusion

165 (14.0)

30 (6.3)

135 (19.1)

38.587

< 0.001

 Nutrition support

131 (11.1)

52 (11.0)

79 (11.2)

0.014

0.906

 TCM treatments

912 (77.0)

418 (88.2)

494 (69.6)

55.620

< 0.001

 Physiotherapy

29 (2.4)

24 (5.1)

5 (0.7)

22.605

< 0.001

Outcomes

 Death, n (%)

62 (5.2)

3 (0.6)

59 (8.3)

33.758

< 0.001

 ICU admission, n (%)

127 (10.7)

30 (6.3)

97 (13.7)

15.961

< 0.001

 Noninvasive mechanical ventilation, n (%)

69 (5.8)

27 (5.7)

42 (5.9)

0.025

0.875

 Invasive mechanical ventilation, n (%)

18 (1.5)

8 (1.7)

10 (1.4)

0.148

0.700

 Time from illness onset to hospitalization, days

8.00 (4.00,13.00)

5.00 (2.00,9.00)

10.00 (7.00,15.00)

13.626

< 0.001

 Hospital stay, days

16.00 (9.00,24.00)

17.00 (12.00,24.00)

14.00 (9.00, 24.00)

−2.726

< 0.001

 Time from illness onset to ICU admission, days

9.00 (6.00,17.00)

7.00 (4.00,10.50)

11.50 (8.75,24.25)

3.192a

< 0.001

 Time from hospitalization to ICU admission, days

3.00 (0.00,9.00)

4.00 (0.00,9.00)

3.00 (0.00,10.50)

0.415

0.678

 Time from illness onset to discharge, days

26.00 (18.00,35.00)

23.00 (18.00,31.00)

28.00 (18.00,38.00)

5.693

< 0.001

 Time from illness onset to death, days

16.50 (13.00,21.75)

13.00 (11, −)

17.00 (13.00,23.50)

1.240a

0.235

 Time from hospital admission to death, days

5.00 (3.00,7.00)

10.00 (6.00,-)

4.00 (3.00,7.00)

1.427

0.153

 Duration of viral shedding, days

14.00 (9.00, 22.00)

13.00 (8.00,18.00)

17.00 (11.00,27.00)

6.665

< 0.001

  1. * Fisher’s exact test
  2. ECMO Extracorporeal membrane oxygenation, TCM Traditional Chinese medicine