|
Case definitions
|
Sensitivity % (95% CI)
|
Specificity % (95% CI)
|
PPV* % (95% CI)
|
NPV† % (95% CI)
|
|---|
|
All cases
|
|
WHO
|
81.0 (77.0–85.0)
|
52.0 (49.1–54.5)
|
32.0 (30.0–35.0)
|
91.0 (89.0–93.1)
|
|
CDC
|
81.0 (77.0–85.1)
|
52.0 (49.1–54.5)
|
32.0 (30.0–35.0)
|
91.0 (88.5–93.1)
|
|
ECDC
|
82.0 (77.5–85.5)
|
50.5 (48.0–53.2)
|
31.2 (28.2–34.2)
|
91.0 (89.0–93.1)
|
|
Age groups (years)
|
|
0 - < 2
|
|
WHO
|
82.0 (70.4–93.2)
|
36.0 (30.0–41.5)
|
18.0 (13.0 -- 23.3)
|
92.0 (87.0–97.3)
|
|
CDC
|
82.0 (70.4–93.2)
|
36.4 (30.6–42.3)
|
18.0 (12.5–23.3)
|
92.2 (86.0–97.4)
|
|
ECDC
|
84.1 (73.3–95.0)
|
36.0 (30.0–41.5)
|
18.2 (13.0–23.5)
|
93.0 (88.0–98.0)
|
|
2 - < 5
|
|
WHO
|
86.0 (78.3–94.0)
|
38.0 (32.3–44.0)
|
28.0 (22.3–33.6)
|
90.5 (85.2–96.0)
|
|
CDC
|
86.0 (77.0–94.0)
|
38.2 (32.5–44.0)
|
28.2 (22.5–34.0)
|
90.6 (85.3–96.0)
|
|
ECDC
|
86.0 (78.2–94.0)
|
38.0 (31.2–43.6)
|
28.0 (22.3–34.0)
|
90.5 (85.1–96.0)
|
|
5 - < 15
|
|
WHO
|
84.0 (77.3–90.1)
|
58.0 (53.2–62.5)
|
37.2 (31.6–42.7)
|
92.2 (89.0–95.4)
|
|
CDC
|
84.4 (78.2–91.0)
|
57.0 (52.3–61.6)
|
37.0 (31.5–42.5)
|
92.5 (89.3–95.6)
|
|
ECDC
|
84.5 (78.2–91.0)
|
56.0 (51.3–61.0)
|
36.5 (31.0–42.0)
|
92.3 (89.1–95.5)
|
|
15 - < 50
|
|
WHO
|
72.0 (62.2–81.3)
|
69.0 (63.3–74.1)
|
41.0 (33.1–49.0)
|
89.0 (85.0–93.2)
|
|
CDC
|
72.0 (62.2–81.3)
|
69.0 (63.6–74.4)
|
41.2 (33.3–49.2)
|
89.0 (85.0–93.1)
|
|
ECDC
|
72.0 (62.2–81.3)
|
66.0 (60.3–71.4)
|
39.0 (31.4–46.6)
|
88.5 (84.2–93.0)
|
|
≥ 50
|
|
WHO
|
81.0 (64.2–980)
|
65.3 (52.0–78.6)
|
50.0 (33.2–67.0)
|
88.5 (78.0–99.1)
|
|
CDC
|
81.0 (64.1–98.0)
|
65.0 (51.0–78.1)
|
50.0 (33.1–67.0)
|
88.6 (78.1–99.2)
|
|
ECDC
|
81.0 (64.1–98.0)
|
65.0 (51.1–78.1)
|
50.0 (33.2–67.0)
|
88.6 (78.1–99.1)
|
- PPV*= Positive Predictive Value; NPV†= Negative Predictive Value
