A real-time PCR assay for rapid identification of inducible and acquired clarithromycin resistance in Mycobacterium abscessus

Table 3 Clarithromycin Minimum Inhibitory Concentration (MIC) interpretations for M. abscessus isolates

	MIC Interpretation
*hsp65* Identification	S	IR	R	Total
M. abscessus subsp. abscessus	22^a	70	2	94^a
M. abscessus subsp. bolletii	2	5	–	7
M. abscessus subsp. massiliense	21	1	1	23
M. abscessus subspecies mixed	2	–	–	2
Total	47	76	3	126

S, Sensitive (MIC ≤2); IR, Inducible Resistance (MIC ≥8 on day 7 or later of susceptibility testing); R, Resistant (MIC ≥8 on day 3 of susceptibility testing); ^a2 mixed cultures of M. abscessus subsp. abscessus, each found to have both wild type T28 and mutation C28 in erm(41)

ISSN: 1471-2334