Table 1 Summary of cases reporting nocardiosis in patients with pemphigus
From: Pulmonary nocardiosis in a patient with pemphigus foliaceus: case report and literature review
Study | Age/gender | Comorbidity | Clinical presentation | Radiological features | Specimen | Nocardia spp. | Antibiotic therapy | Tapering dose of corticosteroids before admission | Outcome |
|---|---|---|---|---|---|---|---|---|---|
Asilian2006 [13] | 56y/man | Chronic bronchitis | Skin abscess, cough and dyspnea | CT: Segmental opacities in the middle zone of the right lung with loculated right pleural effusion | Pleural fluid and sample of skin abscesses | UA | Cotrimoxazole:50 mg/kg/day, i.v | Yes | Improved |
Murdock1990 [14] | 50y/woman | Diabetes mellitus | Sore throat, cough,chest pain,fever, chills | CXR: A large cavitary lesion and an infiltrate in the right upper lung | Sputum | Nocardia brasiliensis | Trimethoprim-sulfamethoxazole: ten days during hospitalization, then minocycline, 100 mg twice a day for 4 months after discharged | No | Improved |
Rahdar2020 [15] | 40y/man | UA | UA | UA | BAL, DNA sequencing | N. cyriacigeorgica | Trimethoprim-sulfamethoxazole: 15 mg/kg/day | UA | Cured |
Rahdar2020 [15] | 41y/man | UA | UA | UA | DNA sequencing | N. cyriacigeorgica | Trimethoprim-sulfamethoxazole: 15 mg/kg/day | UA | Cured |
Rahdar2020 [15] | 39y/man | UA | UA | UA | DNA sequencing | N. otitidiscaviarum | Trimethoprim-sulfamethoxazole: 15 mg/kg/day | UA | Cured |
Rahdar2020 [15] | 58y/man | UA | UA | UA | BAL, DNA sequencing | N. cerradoensis | Trimethoprim-sulfamethoxazole: 15 mg/kg/day | UA | Cured |
Miller1967 [16] | UA/woman | UA | Lethargy and malaise | CXR: A left suprahilar mass and pleural effusion | Pleural fluid | UA | Sulfisoxazole:8 mg daily | Yes | Improved |
Martin2000 [17] | 58y/man | Hypertension | Cough,fever and low level of consciousness | Diffuse cerebral lesions | Lung and brain biopsies | UA | Cefuroxime and Ciprofloxacin | UA | Died |
Chosidow1990 [18] | 57y/woman | Breast malignancy, rheumatoid arthritis and diabetes mellitus | Fever, shivers generalwasting and skin abscess | CXR: A middle-lobe nodular density CT: Hypodensity of the third segment of the liver | Skin biopsy and blood cultures | UA | Trimethoprim-sulfamethoxazole: 400 and 2400 mg/day, Amikacin: 500 mg/day | Yes | Improved |
Present case | 54y/man | Diabetes mellitus | Fever,breathlessness,chest pain | CT: Thick-walled cavities existed in multi-lobes of both lungs | Sputum,BAL, RNA sequencing | Nocardia brasiliensis | Trimethoprim-sulfamethoxazole, intravenous Cefotaxime and Amikacin | Yes | Improved |