WHO weight-band | Initiated under Protocol v3.0 | Initiated under Protocol v4.0 |
---|---|---|
3 to < 6 kg | – | Single PK Curve on 5 mg or 10 mg DTa |
6 to < 10 kg | – | Single PK Curve on 15 mg DT |
10 to < 14 kg | – | Single PK Curve on 20 mg DT |
14 to < 20 kg | Single PK Curve on 25 mg FCT | Single PK Curve on 25 mg DTb |
20 to <25 kg | Single PK Curve on 25 mg FCT | Single PK Curve on 30 mg DT or 50 mg FCTb |
25 to < 30 kg | Cross-over PK with one curve on 25 mg FCT and second curve on 50 mg FCT | – |
30 to < 35 kg | Cross-over PK with one curve on 35 mg FCT and second curve on 50 mg FCT | – |
35 to < 40 kg | Cross-over PK with one curve on 35 mg FCT and second curve on 50 mg FCT | – |
≥40 kg | – | – |