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Table 2 Concentrations of neopterin and amino acids from the study population divided into two groups based on disease severity

From: Serum neopterin levels in relation to mild and severe COVID-19

  Mild (n = 15)
Mean (SD)
Severe (n = 19)
Mean (SD)
p-value
Days since onset 10.2 (9.0) 11.7 (5.8)  
Neopterin, nmol/L 16.9 (11.0) 42.0 (18.2) p < 0.0001
Tryptophan, μmol/L 56.3 (11.6) 31.9 (13.0) p < 0.0001
Kynurenine, μmol/L 2.6 (0.7) 4.3 (1.4) p < 0.0001
KYN/TRP *1000 47.5 (15.1) 163.4 (117.5) p < 0.0001
IFN-y, pg/mL 6.7 (5.0) 21.4 (20.8) p < 0.001
  1. Means and standard deviations (SD) are shown
  2. KYN/TRP kynurenine to tryptophan ratio, IFN-y interferon-gamma