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Table 1 Timeline with the main clinical events and interventions

From: Non-toxigenic Corynebacterium diphtheriae infective endocarditis with embolic events: a case report

Time

Day 0

Day 4

Day 10

Day 15

Day 23

Day 32

Events

• Hospitalization

• Mitral endocarditis diagnosis

• Acute left tibial artery occlusion

• Septic shock

• Sustained fever

• Severe mitral regurgitation

• Daily fever

• Splenic abscess diagnosis

• Recurrent fever

• Persistence of splenic abscess

• Distal left lower limb gangrene

• Clinical recovery

Interventions

• Orotracheal intubation and mechanical ventilation

• Antimicrobial therapy

• Vascular thrombectomy

• Mitral valve replacement surgery

• Percutaneous splenic drainage

• Surgical splenectomy

• Left forefoot amputation

• Hospital discharge