Table 1 Demographic and Laboratory characteristics of all the study participants
Characteristics | HbAA (n = 148) | HbAS (n = 45) | HbSS (n = 24) | P-value+ | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Malaria positive (n = 58) | Malaria Negative (n = 90) | P-value | Malaria Positive (n = 14) | Malaria Negative (n = 31) | P-value | Malaria Positive (n = 13) | Malaria Negative (n = 11) | P value | ||
Sex, n (%) Male | 32 (55.2%) | 50 (55.6%) | 0.964a | 7 (50%) | 15 (48.4%) | 0.921a | 5 (38.5%) | 8 (72.7%) | 0.167a | 0.880a |
Female | 26 (44.8%) | 40 (44.4%) | 7 (50%) | 16 (51.6%) | 8 (62.5%) | 3 (27.3%) | Â | |||
Age, (Months) | 36 (63.3) | 29.5 (37) | 0.022b | 36 (32.3) | 36 (50) | 0.731b | 31 (76) | 16 (27) | 0.569b | 0.507c |
Red cell parameters and its indices | ||||||||||
 Haemoglobin, gdL-1 | 10.2 (2.2) | 10.5 (2.2) | 0.190b | 10.4 (1.6) | 10.8 (2.3) | 0.659b | 7.3 (1.3) | 9.2 (2.8) | 0.018b | 0.001c |
 Haematocrit, % | 34.6 (8.3) | 35.1 (5.7) | 0.356b | 32.9 (6.0) | 36.8 (9.7) | 0.185b | 26.4 (4.4) | 33.7 (6.8) | 0.002b | 0.001c |
 RBC, (× 1012 μL-1) | 4.6 (1.0) | 4.8 (0.7) | 0.302b | 4.8 (1.5) | 5.0 (1.3) | 0.532b | 3.2 (1.7) | 4.7 (1.2) | 0.167b | 0.004c |
 RDW, % | 11.4 (2.2) | 11.2 (2.2) | 0.817b | 11.5 (2.6) | 11.7 (3.6) | 0.589b | 14.9 (3.3) | 12.1 (10.3) | 0.910b | 0.007c |
 MCV, fL | 75.1 (10.5) | 75.7 (11.2) | 0.327b | 74.1 (11.8) | 76.3 (17.3) | 0.540b | 79.5 (15.9) | 76.8 (7.3) | 1.000b | 0.332c |
MCH, fL/cell | 22.15 (3.7) | 22.9 (3.5) | 0.277b | 31.0 (1.7) | 28.6 (3.2) | 0.440b | 23.1 (3.5) | 22.5 (3.7) | 0.569b | 0.784c |
MCHC, gdL-1 | 29.7 (2.2) | 29.9 (4.1) | 0.574b | 31.0 (1.7) | 28.6 (3.2) | 0.008b | 27.7 (4.1) | 28.2 (2.4) | 1.00b | 0.179c |
Leucocyte parameters | ||||||||||
 WBC(×103 μL-1) | 7.8 (4.8) | 8.46 (5.5) | 0.817b | 9.58 (5.2) | 8.3 (5) | 0.433b | 12.68 (4.6) | 12.2 (7.0) | 0.569b | 0.004c |
 Lymphocytes, % | 36.6 (27.2) | 45.1 (24.3) | 0.050b | 37 (36.2) | 43.6 (34.2) | 0.844b | 50.9 (29.1) | 39.6 (17.8) | 0.733b | 0.873c |
 Monocytes, % | 11.2 (7.4) | 9.7 (4.6) | 0.300b | 12 (7.8) | 8.4 (4.8) | 0.140b | 8.1 (6.1) | 9.3 (3.5) | 0.865b | 0.866c |
 Granulocytes, % | 51.5 (27.2) | 45.6 (26.4) | 0.186b | 48.9 (27.5) | 46.1 (28.1) | 0.844b | 39.3 (28.2) | 51.1 (16.4) | 0.649b | 0.833c |
Platelet parameter and its indices | ||||||||||
 Platelet, (×103 μL-1) | 220 (127) | 271 (116) | 0.001b | 232 (129) | 288 (102) | 0.061b | 236 (140) | 265 (187) | 0.955b | 0.001c |
 MPV, fL | 5.4 (0.6) | 5.5 (0.5) | 0.321b | 5.3 (0.9) | 5.5 (0.7) | 0.258b | 5.2 (0.8) | 5.5 (0.6) | 0.733b | 0.710c |
 PDW, % | 9.6 (1.4) | 9.35 (1.5) | 0.632b | 9.5 (1.9) | 9.5 (1.5) | 0.556b | 9.5 (0.4) | 9 (1.5) | 0.277b | 0.611c |
 PCT, % | 0.13 (0.1) | 0.15 (0.1) | 0.003b | 0.1 (0.1) | 0.2 (0.1) | 0.102b | 0.1 (0.1) | 0.15 (0.1) | 0.649b | 0.260c |