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Table 2 Univariable and multivariable logistic regression models of factors associated with Cytomegalovirus seropositivity in England in 2002

From: Factors associated with cytomegalovirus serostatus in young people in England: a cross-sectional study

   Whole-population Adults onlya
Univariable OR (95% CI) Multivariable aOR (95% CI) Multivariable aOR (95% CI)
Sex
 Male 1.00 1.00 1.00
 Female 1.44 (1.02–2.02) 1.39 (0.95–2.05) 1.50 (0.95–2.35)
Age at last birthday (years)
 11–14 1.00 1.00  
 15–18 1.46 (0.89–2.40) 1.55 (0.88–2.75) 1.00
 19–21 1.54 (0.89–2.66) 2.24 (1.21–4.14) 1.05 (0.58–1.91)
 22–24 1.76 (1.04–2.99) 1.77 (0.95–3.29) 0.74 (0.38–1.46)
Ethnicity
 White 1.00 1.00 1.00
 Other 6.75 (4.23–10.77) 6.22 (3.47–11.14) 6.98 (3.18–15.32)
BMI
 Underweight 1.39 (0.77–2.52) 1.18 (0.62–2.24) 0.98 (0.50–1.93)
 Healthy weight 1.00 1.00 1.00
 Overweight 1.11 (0.71–1.74) 1.15 (0.71–1.86) 0.84 (0.47–1.53)
 Obese 1.52 (0.90–2.56) 1.50 (0.81–2.77) 1.06 (0.40–2.76)
EBV serostatus
 Negative 1.00 1.00 1.00
 Positive 1.59 (1.06–2.39) 1.21 (0.76–1.92) 2.08 (1.06–4.09)
Region of England
 East of England 1.00 1.00 1.00
 North East 0.54 (0.18–1.66) 0.51 (0.17–1.50) 0.57 (0.16–2.02)
 North West 0.61 (0.31–1.19) 0.62 (0.31–1.22) 0.60 (0.25–1.40)
 Yorkshire and The Humber 0.70 (0.33–1.51) 0.67 (0.30–1.51) 0.62 (0.26–1.47)
 East Midlands 0.51 (0.21–1.19) 0.52 (0.21–1.26) 0.70 (0.24–2.04)
 West Midlands 0.76 (0.35–1.63) 0.81 (0.36–1.79) 0.53 (0.18–1.60)
 London 2.28 (1.13–4.61) 1.18 (0.52–2.69) 1.28 (0.45–3.61)
 South East 0.50 (0.24–1.03) 0.43 (0.20–0.93) 0.44 (0.17–1.14)
 South West 0.89 (0.46–1.70) 1.09 (0.55–2.15) 0.72 (0.29–1.78)
Smoking statusa
 Never smoked 1.00 1.00
 Current smoker 0.91 (0.54–1.51) 1.08 (0.58–2.01)
 Smoked in past 0.84 (0.51–1.38) 0.96 (0.54–1.69)
Occupational categorya
 Higher managerial and professional 1.00 1.00
 Intermediate occupations 0.88 (0.44–1.76) 0.66 (0.31–1.42)
 Routine and manual occupations 0.68 (0.40–1.18) 0.63 (0.32–1.24)
 Never worked or long-term unemployed 0.48 (0.09–2.45) 0.40 (0.07–2.14)
 Other 0.94 (0.46–1.93)   0.47 (0.17–1.28)
  1. aAdults aged ≥16 years only (n = 472). 16–18 years for ‘adult-only’ model. Odds ratios account for the weighting of the sample to be representative of the English population in 2002 with respect to age and sex. The ‘whole population’ multivariable model included age, sex, CMV serostatus, ethnicity, BMI and region of England. The ‘adults only’ multivariable model included all variables shown in the table. aOR adjusted odds ratio, BMI body mass index, CI confidence interval, CMV cytomegalovirus, OR unadjusted odds ratio