| | |
Whole-population
|
Adults onlya
|
|---|
|
Univariable OR (95% CI)
|
Multivariable aOR (95% CI)
|
Multivariable aOR (95% CI)
|
|---|
|
Sex
|
|
Male
|
1.00
|
1.00
|
1.00
|
|
Female
|
1.44 (1.02–2.02)
|
1.39 (0.95–2.05)
|
1.50 (0.95–2.35)
|
|
Age at last birthday (years)
|
|
11–14
|
1.00
|
1.00
| |
|
15–18†
|
1.46 (0.89–2.40)
|
1.55 (0.88–2.75)
|
1.00
|
|
19–21
|
1.54 (0.89–2.66)
|
2.24 (1.21–4.14)
|
1.05 (0.58–1.91)
|
|
22–24
|
1.76 (1.04–2.99)
|
1.77 (0.95–3.29)
|
0.74 (0.38–1.46)
|
|
Ethnicity
|
|
White
|
1.00
|
1.00
|
1.00
|
|
Other
|
6.75 (4.23–10.77)
|
6.22 (3.47–11.14)
|
6.98 (3.18–15.32)
|
|
BMI
|
|
Underweight
|
1.39 (0.77–2.52)
|
1.18 (0.62–2.24)
|
0.98 (0.50–1.93)
|
|
Healthy weight
|
1.00
|
1.00
|
1.00
|
|
Overweight
|
1.11 (0.71–1.74)
|
1.15 (0.71–1.86)
|
0.84 (0.47–1.53)
|
|
Obese
|
1.52 (0.90–2.56)
|
1.50 (0.81–2.77)
|
1.06 (0.40–2.76)
|
|
EBV serostatus
|
|
Negative
|
1.00
|
1.00
|
1.00
|
|
Positive
|
1.59 (1.06–2.39)
|
1.21 (0.76–1.92)
|
2.08 (1.06–4.09)
|
|
Region of England
|
|
East of England
|
1.00
|
1.00
|
1.00
|
|
North East
|
0.54 (0.18–1.66)
|
0.51 (0.17–1.50)
|
0.57 (0.16–2.02)
|
|
North West
|
0.61 (0.31–1.19)
|
0.62 (0.31–1.22)
|
0.60 (0.25–1.40)
|
|
Yorkshire and The Humber
|
0.70 (0.33–1.51)
|
0.67 (0.30–1.51)
|
0.62 (0.26–1.47)
|
|
East Midlands
|
0.51 (0.21–1.19)
|
0.52 (0.21–1.26)
|
0.70 (0.24–2.04)
|
|
West Midlands
|
0.76 (0.35–1.63)
|
0.81 (0.36–1.79)
|
0.53 (0.18–1.60)
|
|
London
|
2.28 (1.13–4.61)
|
1.18 (0.52–2.69)
|
1.28 (0.45–3.61)
|
|
South East
|
0.50 (0.24–1.03)
|
0.43 (0.20–0.93)
|
0.44 (0.17–1.14)
|
|
South West
|
0.89 (0.46–1.70)
|
1.09 (0.55–2.15)
|
0.72 (0.29–1.78)
|
|
Smoking statusa
|
|
Never smoked
|
1.00
|
–
|
1.00
|
|
Current smoker
|
0.91 (0.54–1.51)
|
–
|
1.08 (0.58–2.01)
|
|
Smoked in past
|
0.84 (0.51–1.38)
|
–
|
0.96 (0.54–1.69)
|
|
Occupational categorya
|
|
Higher managerial and professional
|
1.00
|
–
|
1.00
|
|
Intermediate occupations
|
0.88 (0.44–1.76)
|
–
|
0.66 (0.31–1.42)
|
|
Routine and manual occupations
|
0.68 (0.40–1.18)
|
–
|
0.63 (0.32–1.24)
|
|
Never worked or long-term unemployed
|
0.48 (0.09–2.45)
|
–
|
0.40 (0.07–2.14)
|
|
Other
|
0.94 (0.46–1.93)
| |
0.47 (0.17–1.28)
|
- aAdults aged ≥16 years only (n = 472). †16–18 years for ‘adult-only’ model. Odds ratios account for the weighting of the sample to be representative of the English population in 2002 with respect to age and sex. The ‘whole population’ multivariable model included age, sex, CMV serostatus, ethnicity, BMI and region of England. The ‘adults only’ multivariable model included all variables shown in the table. aOR adjusted odds ratio, BMI body mass index, CI confidence interval, CMV cytomegalovirus, OR unadjusted odds ratio
