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Table 1 Distribution of SCCmec types according to antibiotic non-susceptibility phenotypes for MRSA isolates (n = 2019)

From: Diversity of SCCmec elements and spa types in South African Staphylococcus aureus mecA-positive blood culture isolates

Antibiotic non-susceptibility phenotype

SCCmec type

I

II

III

IV

V

VI

Untypeable

Negative

Erythromycin

0

133 (6.58%)

920 (45.56%)

391 (19.36%)

4 (0.19%)

2 (0.09%)

249 (12.33%)

2 (0.09%)

Clindamycin

1 (0.04%)

129 (6.38%)

106 (5.25%)

31 (1.53%)

0

4 (0.19%)

30 (1.48%)

0

Oxacillin

2 (0.09%)

135 (6.68%)

916 (45.36%)

648 (32.09%)

7 (0.34%)

9 (0.44%)

271 (13.42%)

2 (0.09%)

Penicillin

2 (0.09%)

138 (6.83%)

926 (45.86%)

651 (32.24%)

7 (0.34%)

9 (0.44%)

274 (13.57%)

2 (0.09%)

Trimethoprim/Sulfamethoxazole

0

12 (0.59%)

883 (43.73%)

542 (26.84%)

2 (0.09%)

3 (0.14%)

42 (2.08%)

2 (0.09%)

Daptomycin

0

0

7 (0.34%)

2 (0.09%)

0

0

2 (0.09%)

0

Linezolid

0

3 (0.14%)

3 (0.14%)

3 (0.14%)

0

0

3 (0.14%)

0

Tetracycline

0

14 (0.69%)

913 (45.22%)

573 (28.38%)

3 (0.14%)

2 (0.09%)

79 (3.91%)

2 (0.09%)

Rifampin

0

14 (0.69%)

62 (3.07%)

571 (28.28%)

1 (0.04%)

2 (0.09%)

19 (0.94%)

2 (0.09%)

Ciprofloxacin

0

134 (6.63%)

917 (45.41%)

589 (29.17%)

4 (0.19%)

3 (0.14%)

76 (3.76%)

2 (0.09%)

Levofloxacin

0

134 (6.63%)

916 (45.36%)

512 (25.35%)

3 (0.14%)

3 (0.14%)

75 (3.71%)

2 (0.09%)

Moxyfloxacin

0

133 (6.58%)

918 (45.46%)

510 (25.26%)

3 (0.14%)

2 (0.09%)

75 (3.71%)

2 (0.09%)

Gentamicin

0

19 (0.94%)

912 (45.17%)

556 (27.53%)

6 (0.29%)

3 (0.14%)

242 (11.98%)

2 (0.09%)

  1. Susceptibility was classified according to CLSI guidelines [26]
  2. Suggested antibiotics approved by the US Food and Drug Administration (FDA) for clinical use were included in the table. Antibiotics excluded were azithromycin as erythromycin is a surrogate for macrolides, cefoxtin as oxacillin is included for MRSA, those that are recommended for urine only as well as those that were not tested for using the MicroScan Gram-positive PM-33 panel. In addition, vancomycin was excluded as all isolates were susceptible