Skip to main content

Table 2 Logistic regression analysis of factors associated with being in a phylogenetic cluster for participants with Genotype 1a or 1b in the ALIVE cohort

From: Factors associated with phylogenetic clustering of hepatitis C among people who inject drugs in Baltimore

Characteristic Total (%)
(n = 508)
Not in Cluster (%) (n = 467) In Cluster (%) (n = 41) Univariate P-value Multivariate P-value
Age (per 10 year decrease) 1.59 (1.15, 2.20) < 0.01 1.57 (0.98, 2.53) 0.06
Female Sex 163 (32.1) 140 (30.0) 23 (56.1) 2.98 (1.56, 5.70) < 0.01 2.32 (1.19, 4.55) 0.01
Race
 Black 441 (86.8) 411 (88.0) 30 (73.1) Ref. Ref.
 Non-black 67 (13.2) 56 (12.0) 11 (26.8) 2.69 (1.28, 5.67) < 0.01 2.42 (0.95, 6.21) 0.07
HCV Genotype
 1a 421 (82.9) 388 (83.1) 33 (80.5) Ref.
 1b 87 (17.1) 76 (16.9) 8 (19.5) 1.70 (0.82, 3.51) 0.15
HIV positive 196 (38.6) 166 (35.5) 30 (73.2) 4.95 (2.42, 10.12) < 0.01 5.67 (2.70, 11.92) < 0.01
High school education or higher 202 (39.8) 184 (39.5) 18 (43.9) 1.20 (0.63, 2.28) 0.58
Homelessnessa 98 (19.3) 91 (19.5) 7 (17.1) 0.85 (0.37, 1.98) 0.71
Shared a syringea 85 (16.7) (79 16.9) 6 (14.6) 0.84 (0.34, 2.07) 0.71
Visit SSP in last month 61 (12.1) 57 (12.5) 3 (7.3) 0.55 (0.17, 1.85) 0.34
Injection drug use behaviorsa
 Any injection drug use 204 (40.2) 189 (40.6) 15 (36.6) 0.85 (0.44, 1.64) 0.62
 Use crack 157 (31.0) 146 (31.3) 11 (26.8) 0.80 (0.39, 1.65) 0.55
 Inject cocaine 112 (22.0) 103 (22.1) 9 (22.0) 1.03 (0.46, 2.32) 0.94
 Inject heroin alone 146 (28.7) 137 (29.3) 9 (22.0) 0.68 (0.31, 1.46) 0.32
 Inject speedball 122 (24.0) 114 (24.4) 8 (19.5) 0.75 (0.34, 1.67) 0.48
Year sample collected
 2005–2009 99 (19.5) 93 (19.9) 6 (14.6) Ref. Ref.
 2010–2014 48 (9.5) 42 (9.0) 6 (14.6) 2.21 (0.67, 7.30) 0.19 1.07 (0.31, 3.76) 0.91
 2016 361 (71.1) 332 (71.1) 29 (70.7) 1.35 (0.53, 3.36) 0.51 2.48 (0.88, 6.99) 0.09
  1. aWithin 6 months of visit
  2. HCV hepatitis c virus, HIV human immunodeficiency virus, SSP syringe service program