Comparison of clinical, para-clinical and laboratory findings in survived and deceased patients with COVID-19: diagnostic role of inflammatory indications in determining the severity of illness

Rokni, Mohsen; Ahmadikia, Kazem; Asghari, Somaye; Mashaei, Shahabodin; Hassanali, Fahimeh

doi:10.1186/s12879-020-05540-3

Table 5 Comparison of inclusion indicators in the survival and deceased groups COVID-19

From: Comparison of clinical, para-clinical and laboratory findings in survived and deceased patients with COVID-19: diagnostic role of inflammatory indications in determining the severity of illness

Blood routine (Unit, Normal range)	Stat	Total (N = 233)	Mean	±Std. Err. Mean	Sig. (2-tailed)
Leucocyte Count (×10⁹/L, range 3.5–9.5)	Deceased	28	12.3	1.17	0.0001**
Leucocyte Count (×10⁹/L, range 3.5–9.5)	Survival	205	6.1	0.23	0.0001**
Platelet Count (× 10⁹/ L, range 125–450)	Deceased	28	202.1	18.1	0.480
Platelet Count (× 10⁹/ L, range 125–450)	Survival	205	215.9	6.56	0.480
Neutrophil Count (×10⁹/ L, range 1.8–6.3)	Deceased	28	11.08	1.12	0.0001**
Neutrophil Count (×10⁹/ L, range 1.8–6.3)	Survival	205	4.69	0.27	0.0001**
Lymphocyte Count (×10⁹/ L, range 1.1–3.2)	Deceased	28	0.79	0.07	0.0001**
Lymphocyte Count (×10⁹/ L, range 1.1–3.2)	Survival	205	1.14	0.04	0.0001**
Neutrophil / Lymphocyte Ratio (index, < 5)	Deceased	28	19.28	2.93	0.0001**
Neutrophil / Lymphocyte Ratio (index, < 5)	Survival	205	4.96	0.34	0.0001**
Platelet / Lymphocyte Ratio (index, < 200)	Deceased	28	343.8	66.4	0.001*
Platelet / Lymphocyte Ratio (index, < 200)	Survival	205	221.7	10.7	0.001*
Systematic Inflammatory Index (index, < 500)	Deceased	28	3532.9	565.3	0.0001**
Systematic Inflammatory Index (index, < 500)	Survival	205	1163.5	102.9	0.0001**
BUN (mg/dL, range 5–24)	Deceased	26	51.2	7.18	0.0001**
BUN (mg/dL, range 5–24)	Survival	199	18.3	0.65	0.0001**
Creatinine (mg/dL, range 0.5–1.4)	Deceased	26	2.22	0.28	0.0001**
Creatinine (mg/dL, range 0.5–1.4)	Survival	197	1.16	0.02	0.0001**
C-Reactive Protein (mg/L, 0.0–6.0)	Deceased	28	15.0	0.79	0.151
C-Reactive Protein (mg/L, 0.0–6.0)	Survival	205	13.2	0.44	0.151
SGOT (IU/L, range 8–40)	Deceased	23	80.1	20.2	0.0001**
SGOT (IU/L, range 8–40)	Survival	179	40.6	2.43	0.0001**
SGPT (IU/L, range 0–64)	Deceased	23	48.8	12.1	0.176
SGPT (IU/L, range 0–64)	Survival	179	37.4	2.61	0.176
Alkaline Phosphatase (IU/L, range 25–320)	Deceased	21	271.5	17.4	0.339
Alkaline Phosphatase (IU/L, range 25–320)	Survival	174	253.1	7.76	0.339
Total Bilirubin (mg/dL, range 0.4–1.3)	Deceased	19	1.44	0.31	0.004*
Total Bilirubin (mg/dL, range 0.4–1.3)	Survival	161	0.91	0.05	0.004*
Direct Bilirubin (mg/dL, range 0.1–0.3)	Deceased	19	0.59	0.21	0.007*
Direct Bilirubin (mg/dL, range 0.1–0.3)	Survival	161	0.31	0.03	0.007*
Creatine Kinase (IU/L, range 12–160)	Deceased	20	438.8	169.3	0.315
Creatine Kinase (IU/L, range 12–160)	Survival	163	258.1	48.1	0.315
Lactate Dehydrogenase (IU/L, range 140–280)	Deceased	18	820.5	122.1	0.001*
Lactate Dehydrogenase (IU/L, range 140–280)	Survival	155	534.4	26.5	0.001*
Sodium (mEq/L, 135–145)	Deceased	25	136.40	1.43	0.698
Sodium (mEq/L, 135–145)	Survival	184	136.04	0.28	0.698
Potassium (mEq/L, 3.5–5.5)	Deceased	25	4.2	0.17	0.001*
Potassium (mEq/L, 3.5–5.5)	Survival	183	3.9	0.03	0.001*
ESR (mm/h, 2–22)	Deceased	15	56.1	4.81	0.048*
ESR (mm/h, 2–22)	Survival	147	46.3	2.17	0.048*
D-Dimer (mg/L; range < 0.55)	Deceased	7	1.24	0.06	0.001*
D-Dimer (mg/L; range < 0.55)	Survival	27	0.64	0.08	0.001*

The values were presented as mean ± SEM. (*P < 0.05, **P ≤ 0.0001)

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