Table 2 Risk factors associated with admission of COVID-19 patients to ICU
Variable | Univariable OR (95% CI, P value) | Multivariable OR (95% CI, P value) |
|---|---|---|
Age (per year increase) | 1.056 (1.041–1.071, P < 0.001) | 1.041 (1.022–1.061, P < 0.001) |
Male sex (versus female) | 2.741 (1.316–5.711, P 0.007) | 4.375 (1.964–9.744, P < 0.001) |
Co-morbidity present (versus not present) | ||
 Diabetes mellitus | 3.461 (2.319–5.164,P < 0.001) | 1.698 (1.050–2.746, P 0.031) |
 Hypertension | 2.919 (1.941–4.340, P < 0.001) | 0.980 (0.589–1.630, P 0.937) |
 Coronary artery disease | 4.180 (1.991–8.778, P < 0.001) | 1.090 (0.449–2.643, P 0.849) |
 Chronic lung disease | 1.717 (0.859–3.430, P 0.126) | .. |
 Chronic liver disease | 3.536 (1.143–10.934, P 0.028) | 2.463 (0.716–8.465, P 0.153) |
 Chronic kidney disease | 8.341 (4.050–17.177, P < 0.001) | 3.590 (1.596–8.079, P 0.002) |
BMI (per one kg/m2 increase) | 1.067 (1.033–1.102, P < 0.001) | 1.067 (1.027–1.108, P 0.001) |
Presenting symptoms (versus not present) | ||
 Fever | 28.542 (9.011–90.401, P < 0.001) |  |
 Cough | 6.145 (3.339–11.312, P < 0.001) |  |
 Dyspnea | 7.879 (5.123–11.909, P < 0.001) |  |
 Sore throat | 0.660 (0.403–1.079, P < 0.001) |  |
 Rhinorrhea | 0.833 (0.0115–0.602, P 0.014) |  |
Baseline vital signa (per unit increase) | ||
 Systolic blood pressure (mmHg) | 0.987 (0.973–1.001, P 0.062) |  |
 Heart rate (beats per minute) | 1.037 (1.024–1.049, P < 0.001) |  |
 Respiratory rate (breaths per minute) | 1.264 (1.217–1.313, P < 0.001) |  |
 Oxygen saturation (%) | 0.651 (0.605–0.701, P < 0.001) |  |
Baseline laboratory results (per unit increase) | ||
 Lymphocytes count (× 109 per L) | 0.155 (0.100–0.240, P < 0.001) |  |
 Platelet count (× 109 per L) | 0.993 (0.990–0.996, P < 0.001) |  |
 Serum sodium (mmol/L) | 0.801 (0.757–0.848, P < 0.001) |  |
 Serum creatinine (μmol/L) | 1.003 (1.001–1.005, P < 0.005) |  |
 CRP (mg/L) | 1.016 (1.013–1.019, P < 0.001) |  |
 ALT (U/L) | 1.001 (0.999–1.002, P 0.2) |  |