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Table 2 Data for the CSF sterility at the 10 weeks follow-up

From: Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure

 

Group I (AmB+

Group II (AmB +

P-value

Fluconazole+ 5-FC,n = 27)

Fluconazole+ 5-FC + VPS, na = 38)

case (n, %)

8 (29.6%)

22 (56.4%)

0.033*

Daysb (mean ± SD)

29.2 ± 20.0

32.5 ± 24.8

0.909

 ≤ 2 weeks (n, %)

2 (7.4%)

8 (20.5%)

0.662

 >  2 weeks (n, %)

6 (22.2%)

14 (35.9%)

 

 ≤ 4 weeks (n, %)

4 (14.8%)

13 (33.3%)

0.730

 >  4 weeks (n, %)

4 (14.8%)

9 (23.1%)

 
  1. AmB amphotericin B, 5-Fc flucytosine, Flu fluconazole, SD standard deviation. Continuous variables analyzed by t-test; categorical variables analyzed by chi-square test or Fisher’s exact test
  2. a One patient was lost to -follow-up at the 10th week in Group II
  3. b‘Days’ indicates the time from diagnosis to the first negative CSF india ink stain
  4. *P < 0.05
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BMC Infectious Diseases

ISSN: 1471-2334

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