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Table 2 Data for the CSF sterility at the 10 weeks follow-up

From: Triple therapy combined with ventriculoperitoneal shunts can improve neurological function and shorten hospitalization time in non-HIV cryptococcal meningitis patients with increased intracranial pressure

  Group I (AmB+ Group II (AmB + P-value
Fluconazole+ 5-FC,n = 27) Fluconazole+ 5-FC + VPS, na = 38)
case (n, %) 8 (29.6%) 22 (56.4%) 0.033*
Daysb (mean ± SD) 29.2 ± 20.0 32.5 ± 24.8 0.909
 ≤ 2 weeks (n, %) 2 (7.4%) 8 (20.5%) 0.662
 >  2 weeks (n, %) 6 (22.2%) 14 (35.9%)  
 ≤ 4 weeks (n, %) 4 (14.8%) 13 (33.3%) 0.730
 >  4 weeks (n, %) 4 (14.8%) 9 (23.1%)  
  1. AmB amphotericin B, 5-Fc flucytosine, Flu fluconazole, SD standard deviation. Continuous variables analyzed by t-test; categorical variables analyzed by chi-square test or Fisher’s exact test
  2. a One patient was lost to -follow-up at the 10th week in Group II
  3. b‘Days’ indicates the time from diagnosis to the first negative CSF india ink stain
  4. *P < 0.05