Table 6 Parameter combinations (numbered 1-27) simulating varying levels of antimicrobial stewardship (Cols 2 and 3) and effective ward-room terminal cleaning (Col 4). The risk-level scenarios in Column 3 (numbered 1-3) are given for reference alongside the corresponding resulting change from median baseline nosocomial colonizations and infections (given in Table 4). Specific distributions of antibiotic-risk level probabilities for each risk scenario are given in Table 3
Scenario number | Half-daily antibiotic probability | Targeted antib reduction scenario | Probability of sufficient cleaning | Change from baseline median colonizations | Change from baseline median infections |
|---|---|---|---|---|---|
1 | 0.27* | 1* | 0.2 | +3.30% | +1.45% |
2 | 0.27* | 1* | 0.5* | 0.00% | 0.00% |
3 | 0.27* | 1* | 0.8 | -2.26% | -2.10% |
4 | 0.27* | 2 | 0.2 | -4.20% | -14.96% |
5 | 0.27* | 2 | 0.5* | -7.93% | -14.90% |
6 | 0.27* | 2 | 0.8 | -10.09% | -17.19% |
7 | 0.27* | 3 | 0.2 | -14.22% | -21.87% |
8 | 0.27* | 3 | 0.5* | -17.45% | - 23.21% |
9 | 0.27* | 3 | 0.8 | -19.70% | -24.32% |
10 | 0.243 | 1* | 0.2 | -6.07% | -3.27% |
11 | 0.243 | 1* | 0.5* | -10.04% | -5.21% |
12 | 0.243 | 1* | 0.8 | -11.70% | -6.36% |
13 | 0.243 | 2 | 0.2 | -13.18% | -16.88% |
14 | 0.243 | 2 | 0.5* | -16.95% | -18.37% |
15 | 0.243 | 2 | 0.8 | -18.75% | -18.25% |
16 | 0.243 | 3 | 0.2 | -22.50% | -24.83% |
17 | 0.243 | 3 | 0.5* | -25.40% | -22.91% |
18 | 0.243 | 3 | 0.8 | -27.79% | -25.37% |
19 | 0.216 | 1* | 0.2 | -16.70% | -5.62% |
20 | 0.216 | 1* | 0.5* | -19.33% | -8.45% |
21 | 0.216 | 1* | 0.8 | -21.49% | -7.94% |
22 | 0.216 | 2 | 0.2 | - 22.44% | -18.60% |
23 | 0.216 | 2 | 0.5* | -26.21% | - 21.21% |
24 | 0.216 | 2 | 0.8 | -27.50% | -20.97% |
25 | 0.216 | 3 | 0.2 | -31.18% | -25.25% |
26 | 0.216 | 3 | 0.5* | -33.72% | -26.19% |
27 | 0.216 | 3 | 0.8 | -35.83% | - 25.90% |