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Table 4 Complications, treatment and outcomes of patients with COVID-19

From: Clinical characteristics of 116 hospitalized patients with COVID-19 in Wuhan, China: a single-centered, retrospective, observational study

Characteristics Total (N = 116) Disease severity PValue
Non-severe (n = 61) Severe (n = 55)
Complications, No./total No. (%)
 Shock 16/116 (13.8) 0/61 (0.0) 16/55 (29.1) < 0.0001
 Acute cardiac injury 23/116 (19.8) 4/61 (6.6) 19/55 (34.5) 0.001
 Acute respiratory distress syndrome 20/116 (17.2) 0/61 (0.0) 20/55 (36.4) < 0.0001
 Liver dysfunction 15/116 (12.9) 2/61 (3.3) 13/55 (23.6) 0.0011
 Acute kidney injury 3/116 (2.6) 0/61 (0.0) 3/55 (5.5) 0.0565
 Acute heart failure 21/116 (18.1) 3/61 (4.9) 18/55 (32.7) 0.0002
Treatment, No./total No. (%)
 Administration of oseltamivir 91/116 (78.4) 46/61 (75.4) 45/55 (81.8) 0.4019
 Administration of lopinave/litonawe (LPV/r) 74/116 (63.8) 42/61 (68.9) 32/55 (58.2) 0.2325
 Administration of arbidolhydrochloride 27/116 (23.3) 15/61 (24.6) 12/55 (21.8) 0.7243
 Administration of ribavirin injection 71/116 (61.2) 37/61 (60.7) 34/55 (61.8) 0.8979
 Administration of antibiotics 113/116 (97.4) 58/61 (95.1) 55/55 (100.0) 0.0956
 Use of antifungal medications 12/116 (10.3) 0/61 (0.0) 12/55 (21.8) 0.0001
 Administration of systemic corticosteroids 55/116 (47.4) 14/61 (23.0) 41/55 (74.5) < 0.0001
 Oxygen inhalation 103/116 (88.8) 50/61 (82.0) 53/55 (96.4) 0.0141
 Noninvasive ventilation 18/116 (15.5) 0/61 (0.0) 18/55 (32.7) < 0.0001
 Invasive mechanical ventilation 10/116 (8.6) 0/61 (0.0) 10/55 (18.2) 0.0005
 Extracorporeal membrane oxygenation 3/116 (2.6) 0/61 (0.0) 3/55 (5.5) 0.0646
 Use of intravenous immunoglobin 74/116 (63.8) 25/61 (41.0) 49/55 (89.1) < 0.0001
 Use of thymopeptidesinjection 92/116 (79.3) 45/61 (73.8) 47/55 (85.5) 0.1209
 Traditional Chinese medical herbal treatment 103/116 (88.8) 55/61 (90.2) 48/55 (87.3) 0.2955
Clinical outcomes, No./total No. (%)
 Discharge from hospital 109/116 (94.0) 61/61 (100.0) 48/55 (87.3) 0.0040
 Death 7/116 (6.0) 0/61 (0.0) 7/55 (12.7) 0.0040