Characteristics | Total (N = 116) | Disease severity | PValue | |
---|---|---|---|---|
Non-severe (n = 61) | Severe (n = 55) | |||
Complications, No./total No. (%) | ||||
 Shock | 16/116 (13.8) | 0/61 (0.0) | 16/55 (29.1) | < 0.0001 |
 Acute cardiac injury | 23/116 (19.8) | 4/61 (6.6) | 19/55 (34.5) | 0.001 |
 Acute respiratory distress syndrome | 20/116 (17.2) | 0/61 (0.0) | 20/55 (36.4) | < 0.0001 |
 Liver dysfunction | 15/116 (12.9) | 2/61 (3.3) | 13/55 (23.6) | 0.0011 |
 Acute kidney injury | 3/116 (2.6) | 0/61 (0.0) | 3/55 (5.5) | 0.0565 |
 Acute heart failure | 21/116 (18.1) | 3/61 (4.9) | 18/55 (32.7) | 0.0002 |
Treatment, No./total No. (%) | ||||
 Administration of oseltamivir | 91/116 (78.4) | 46/61 (75.4) | 45/55 (81.8) | 0.4019 |
 Administration of lopinave/litonawe (LPV/r) | 74/116 (63.8) | 42/61 (68.9) | 32/55 (58.2) | 0.2325 |
 Administration of arbidolhydrochloride | 27/116 (23.3) | 15/61 (24.6) | 12/55 (21.8) | 0.7243 |
 Administration of ribavirin injection | 71/116 (61.2) | 37/61 (60.7) | 34/55 (61.8) | 0.8979 |
 Administration of antibiotics | 113/116 (97.4) | 58/61 (95.1) | 55/55 (100.0) | 0.0956 |
 Use of antifungal medications | 12/116 (10.3) | 0/61 (0.0) | 12/55 (21.8) | 0.0001 |
 Administration of systemic corticosteroids | 55/116 (47.4) | 14/61 (23.0) | 41/55 (74.5) | < 0.0001 |
 Oxygen inhalation | 103/116 (88.8) | 50/61 (82.0) | 53/55 (96.4) | 0.0141 |
 Noninvasive ventilation | 18/116 (15.5) | 0/61 (0.0) | 18/55 (32.7) | < 0.0001 |
 Invasive mechanical ventilation | 10/116 (8.6) | 0/61 (0.0) | 10/55 (18.2) | 0.0005 |
 Extracorporeal membrane oxygenation | 3/116 (2.6) | 0/61 (0.0) | 3/55 (5.5) | 0.0646 |
 Use of intravenous immunoglobin | 74/116 (63.8) | 25/61 (41.0) | 49/55 (89.1) | < 0.0001 |
 Use of thymopeptidesinjection | 92/116 (79.3) | 45/61 (73.8) | 47/55 (85.5) | 0.1209 |
 Traditional Chinese medical herbal treatment | 103/116 (88.8) | 55/61 (90.2) | 48/55 (87.3) | 0.2955 |
Clinical outcomes, No./total No. (%) | ||||
 Discharge from hospital | 109/116 (94.0) | 61/61 (100.0) | 48/55 (87.3) | 0.0040 |
 Death | 7/116 (6.0) | 0/61 (0.0) | 7/55 (12.7) | 0.0040 |