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Table 3 Characteristics and outcomes of pregnant women with confirmed drug-resistant tuberculosis (n=8)

From: Tuberculosis clinical presentation and treatment outcomes in pregnancy: a prospective cohort study

Participant Age TB Presentation Baseline DST profile TB treatment regimen Treatment Outcome
1 19 • Smear +++ pulmonary TB
• No history of TB
• Cavity seen on CXR
• Cough, cough with blood, cough with phlegm, weight loss, difficulty breathing
MDR (Resistant: INH, RIF, SM) CS
EMB ETH LEVO PZA
Treatment completed
2 21 • Smear + pulmonary TB
• History of TB
• Cough, cough with phlegm, difficulty breathing, night sweats
MDR
(Resistant: INH, RIF, SM)
CS
EMB ETH LEVO PZA
Lost to follow up
3 29 • Smear – pulmonary TB
• No history of TB
• Cough, cough with blood, cough with phlegm, difficulty breathing, night sweats
Mono-resistant (Resistant SM) EMB
INH PZA
RIF
Cured
4 30 • Smear – pulmonary TB
• No history of TB
• Cough, cough with blood, cough with phlegm, weight loss, difficulty breathing, night sweats
Mono-resistant (Resistant: EMB) EMB INH PZA
RIF
Cured
5 34 • Smear ++ pulmonary TB
• History of TB
• Cough, cough with phlegm, weight loss
MDR (Resistant: PZA, INH, EMB, RIF, SM) CS LEVO PAS PZA Cured
6 17 • Smear ++ pulmonary TB
• No history of TB
• History of asthma
• Difficulty breathing, night sweats
Mono-resistant (Resistant: SM) EMB INH LEVO PZA Cured
7 33 • Smear + pulmonary TB
• History of TB
• Cough, cough with phlegm, weight loss
Mono-resistant (Resistant: RIF)a EMB INH PZA
RIF
Cured
8 25 • Smear +++ pulmonary TB
• No history of TB
• Cough, cough with blood, cough with phlegm, weight loss
MDR (Resistant: INH, EMB, RIF, SM) EMB INH PZA
RIF
Treatment completed
  1. Abbreviations: CXR chest x-ray, CS cycloserine, EMB ethambutol, ETH ethionamide, LEVO levofloxacin, PZA pyrazinamide, INH isoniazid, RIF rifampin, SM streptomycin
  2. aRIF resistance was detected on a second drug susceptible test