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Table 2 The diagnostic evaluation of induration and erythema after EC skin test

From: Induration or erythema diameter not less than 5 mm as results of recombinant fusion protein ESAT6-CFP10 skin test for detecting M. tuberculosis infection

Diagnostic index

Different times

χ2

P

24 h

48 h

72 h

Induration results

 Sensitivity

72.14%a

84.25%

83.78%

43.80

<  0.01

 Specificity

97.49%a

91.15%

56.81

<  0.01

 PV+

93.38%a

82.37%

35.30

<  0.01

 PV

87.70%a

92.18%

17.41

<  0.01

 Consistency

89.14%a

88.88%

0.08

0.78

 YI

69.63%

75.40%

  

 Kappa (95% CI)

0.74 (0.71, 0.77)

0.75 (0.72, 0.78)

  

Erythema results

 Sensitivity

85.33%a

90.85%

91.08%

16.18

<  0.01

 Specificity

95.38%a

89.83%

34.02

<  0.01

 PV+

90.06%a

81.42%

22.74

<  0.01

 PV

92.98%a

95.24%

6.78

0.01

 Consistency

92.07%a

90.16%

5.06

0.02

 YI

80.71%

80.68%

  

 Kappa (95% CI)

0.82 (0.79, 0.85)

0.78 (0.75, 0.81)

  
  1. PV+ Positive predict value, PV Negative predict value, YI Youden index
  2. acompared with 48 h and 72 h or compared with 48 h