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Table 1 Published cases of interstitial pneumonitis secondary to intravesical BCG

From: Disseminated Bacillus Calmette–Guérin (BCG) infection and acute exacerbation of interstitial pneumonitis: an autopsy case report and literature review

Reference Case Age BCC treatment before onset Time from final BCC treatment to onset Time from final BCC treatment to dyspnea Antituberculosis Steroid Other symptoms Prognosis
Diner [10] 1 81 6 weeks + 4 weeks of maintenance 1 day 2 weeks INH + RFP + EB PSL 30 mg Fever Alive
Cho [6] 2 76 Not specified 7 months 7 months INH + RFP + EB Pulse Fever, pancytopenia Alive
Lyons [11] 3 78 4 weeks 6 h 3 weeks INH + RFP PSL 40 mg Fever, hepatitis Alive
Carrasco [12] 4 73 8 times 10 days Not specified Not specified mPSL 40 mg Fever, hepatitis Alive
Um [3] 5 60 3 times 3 weeks 3 weeks Not specified cortisteroid Fever, hepatitis Alive
Naoki [13] 6 61 3 times 1 week 3 weeks INH + RFP + EB Pulse Fever, hepatitis Alive
Nitta [14] 7 60 6 times + maintenance BCG 1 day 2 weeks INH + RFP + EB Pulse Fever Alive
Horinaga [15] 8 61 3 times Not specified Not specified INH + RFP + SM Pulse Fever, hepatitis Alive
Uetsuki [16] 9 49 8 times+ 5 times Not specified Not specified INH + RFP Pulse Fever, hepatitis Alive
Yamamoto [17] 10 81 5 times 1 week 2 weeks INH + RFP Pulse Fever Died
Davis [18] 11 79 7 times 1 week 12 days INH + RFP + EB PSL 60 mg Fever Alive
Tobiume [19] 12 86 3 times 6 days 6 days INH + RFP Pulse Fever Alive
Caravaca [20] 13 81 1 time 30 days Not specified INH + RFP + EB Not used (TAC + EVL) Fever Alive
Azumi [21] 14 73 6 times + 2 times Not specified 50 days after admission INH + RFP + EB Pulse Fever, nephromegaly Died
Kitani [22] 15 85 3 times The same day The same day Not used PSL 250 mg Fever Alive
Kazuaki [23] 16 72 6 times 1 weeks 2 weeks Not used Pulse nausea Died