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Table 4 Sensitivity comparisons of plasma IS6110 & IS1081-dPCR assay with routine diagnostic tests in diagnosis of TB

From: Evaluation of digital PCR assay in detection of M.tuberculosis IS6110 and IS1081 in tuberculosis patients plasma

Methods Number of TB Patients Sensitivity p value
IS6110 & IS1081-dPCR vs Smear microscope 108 38.0% (41/108) vs 93.5% (101/108) 0.000
IS6110 & IS1081-dPCR vs Mycobacterial culture 66 34.8% (23/66) vs 97.0% (64/66) 0.000
IS6110 & IS1081-dPCR vs IS6110 qPCR 40 57.5% (23/40) vs 22.5% (9/40) 0.031
  1. qPCR quantitative polymerase chain reaction; McNemar test was used to calculate p value