Ā | Cut-off point (copies/20āĪ¼l) | AUC | Sensitivity(%) | Specificity(%) | LR+ | LR- | PPV(%) | NPV(%) |
---|---|---|---|---|---|---|---|---|
Disseminated TB (16) compared with HC (nĀ =ā106) | ||||||||
āIS6110-dPCR | 16 | 0.98 (0.97ā1.00) | 77.8 (47.6ā92.7) | 99.1 (94.9ā100.0) | 86.1 (12.1ā614.4) | 0.2 (0.1ā0.5) | 92.9 (64.7ā99.9) | 97.2 (92.1ā99.4) |
āIS1081-dPCR | 14 | 0.95 (0.91ā0.99) | 37.5 (16.2ā64.6) | 99.1 (94.9ā100.0) | 39.8 (5.1ā309.0) | 0.6 (0.4ā0.9) | 85.7 (38.1ā99.8) | 91.3 (84.6ā95.8) |