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Table 2 Clinical presentation at the newborn unit for infants with early onset sepsis, by antibiotic treatment group; Guideline (n = 1172) and Non-Guideline (n = 354)

From: Adherence to World Health Organisation guidelines for treatment of early onset neonatal sepsis in low-income settings; a cohort study in Nepal

Characteristics of cases Guideline
n (valid %)
Non-guideline
n (valid %)
p-value
Lethargy 167 (19.2) 39 (12.3) < 0.01
Tachypnoea (> 60 breaths per minute) 357 (31.7) 61 (17.9) < 0.01
Seizures 41 (4.6) 9 (2.8) 0.18
Grunting 134 (14.8) 13 (4.2) < 0.01
Apnoea 19 (2.1) 2 (0.7) 0.13a
Fever (> 38 degrees Celsius) 494 (44.4) 120 (35.5) < 0.01
Hypothermia (< 35.5 degrees Celsius) 9 (0.9) 4 (1.2) 0.75a
Severe chest indrawing 27 (3.1) 3 (1.0) 0.06a
Central cyanosis 31 (3.5) 3 (0.9) 0.02a
Severe jaundice (palms and soles yellow) 14 (1.66) 4 (1.26) 0.79
  1. aFisher exact test