Table 3 Liver tissue characteristics of PEG-IFN-α treated CHB patients

Fibrosis stage (METAVIR)

1.63 ± 0.83

1.19 ± 0.86*

Inflammation stage (METAVIR)

2.19 ± 0.74

1.5 ± 0.72*

CD4⁺ T cells (%) (median)

16.5 (10.16–23.94)

12.55 (7.6–19)

CD8⁺ T cells (%) (median)

2.18 (1.23–3.98)

0.62 (0.27–2.46)**

CD68⁺ cells (%) (median)

1.39 (0.61–3.63)

1.16 (0.16–4.36)

PD-1⁺ cells (%) (median)

0.5 (0.10–0.90)

0.29 (0.08–0.64)