Table 1 Demographic and clinical characteristics of patients with COVID-19 at admissiona
| Â | Severe/Critically ill | ||||
|---|---|---|---|---|---|
Category | Characteristics | Yes (N = 64) | No (N = 561) | All (N = 625) | P-value |
Demographic, n/N (%), N, mean (SD) | |||||
| Â | Male | 41/64(64.1%) | 288/561(51.3%) | 329/625(52.6%) | 0.0534 |
| Â | Female | 23/64(35.9%) | 273/561(48.7%) | 296/625(47.4%) | Â |
| Â | Age (year) | 64,59.53(13.43) | 561,42.72(16.73) | 625,44.44(17.19) | <.0001 |
|  | ≤18 years | 0/64(0.0%) | 37/561(6.6%) | 37/625(5.9%) | <.0001 |
|  | 19–44 years | 6/64(9.4%) | 255/561(45.5%) | 261/625(41.8%) |  |
|  | 45–64 years | 32/64(50.0%) | 216/561(38.5%) | 248/625(39.7%) |  |
| Â | 65+ years | 26/64(40.6%) | 53/561(9.4%) | 79/625(12.6%) | Â |
Exposure type, n/N (%) | |||||
| Â | Imported cases | 25/64(39.1%) | 194/561(34.6%) | 219/625(35.0%) | 0.4765 |
| Â | Local cases | 39/64(60.9%) | 367/561(65.4%) | 406/625(65.0%) | Â |
Types of disease onset, n/N (%) | |||||
| Â | Single onset | 40/64(62.5%) | 270/561(48.1%) | 310/625(49.6%) | 0.0294 |
| Â | Clustering onset | 24/64(37.5%) | 291/561(51.9%) | 315/625(50.4%) | Â |
Initial symptoms, n/N (%) | |||||
| Â | Fever | 52/64(81.3%) | 360/561(64.2%) | 412/625(65.9%) | 0.0063 |
| Â | Cough | 44/64(68.8%) | 300/561(53.5%) | 344/625(55.0%) | 0.0200 |
| Â | Sputum | 25/64(39.1%) | 141/561(25.1%) | 166/625(26.6%) | 0.0168 |
Medical history, n/N (%) | |||||
| Â | Hypertension | 19/64(29.7%) | 72/561(12.8%) | 91/625(14.6%) | 0.0003 |
| Â | Diabetes | 10/64(15.6%) | 30/561(5.3%) | 40/625(6.4%) | 0.0015 |
| Â | Stroke | 2/64(3.1%) | 8/560(1.4%) | 10/624(1.6%) | 0.2736 |
Vital signs, N, mean (SD) | |||||
|  | Temperature (°C) | 64,37.30(0.94) | 561,37.02(0.70) | 625,37.05(0.73) | 0.0040 |
| Â | HR (bpm) | 64,89.98(15.06) | 561,86.84(13.25) | 625,87.17(13.46) | 0.0772 |
| Â | Respiratory rate (breath per min) | 64,20.98(4.87) | 561,18.87(2.04) | 625,19.08(2.56) | <.0001 |
| Â | SpO2 (%) | 64,95.53(4.70) | 561,97.92(1.15) | 625,97.68(1.99) | <.0001 |
CT image, N, median (IQR) | |||||
|  | Quadrant score (1–4) | 58,4.0(4.0–4.0) | 438,2.0(1.0–4.0) | 496,2.0(1.0–4.0) | <.0001 |
|  | Pulmonary opacity (%) | 58,50.0(35.0–70.0) | 438,20.0(5.0–30.0) | 496,20.0(5.0–40.0) | <.0001 |
Laboratory test, N, median (IQR) | |||||
|  | WBC Count (109/L) | 52,4.3(3.4–5.8) | 461,5.0(4.0–6.3) | 513,4.9(3.9–6.2) | 0.0440 |
|  | Neutrophil (109/L) | 52,2.9(2.0–4.4) | 455,3.0(2.2–4.0) | 507,3.0(2.2–4.0) | 0.7435 |
|  | Lymphocyte (109/L) | 52,0.7(0.5–1.0) | 453,1.4(1.0–1.8) | 505,1.3(0.9–1.7) | <.0001 |
|  | Platelet (109/L) | 48,154.0(118.0–185.0) | 446,188.5(154.0–222.0) | 494,183.5(151.0–219.0) | <.0001 |
|  | Albumin (g/L) | 48,39.7(34.2–41.4) | 432,42.0(38.0–45.7) | 480,41.4(38.0–45.1) | <.0001 |
|  | Creatinine (umol/L) | 49,64.0(51.0–83.0) | 427,63.8(51.0–79.0) | 476,63.9(51.0–79.0) | 0.6950 |
|  | C-reactive protein (mg/L) | 44,40.1(8.6–92.7) | 430,10.0(2.6–19.3) | 474,10.0(2.7–22.6) | <.0001 |
|  | Activated partial thromboplastin time (s) | 54,32.6(28.5–36.5) | 459,32.2(27.9–37.4) | 513,32.2(28.0–37.2) | 0.8158 |
|  | Fibrinogen (g/L) | 53,4.3(3.2–5.9) | 443,3.4(2.7–4.1) | 496,3.5(2.7–4.2) | <.0001 |
|  | D-dimer (mg/L) | 51,0.3(0.2–1.0) | 424,0.2(0.1–0.4) | 475,0.2(0.1–0.4) | 0.0003 |