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Table 4 Univariate and Multivariable Analysis of Factors Associated with TBI Treatment Completion

From: Gaps in the care cascade for screening and treatment of refugees with tuberculosis infection in Middle Tennessee: a retrospective cohort study

  Univariate Multivariable
OR 95% CI p OR 95% CI p
Elixhauser Comorbidity Indexa
No Comorbidity (Score = 0) ref      
Any Comorbidity (Score ≥ 1) 1.10 [0.77,1.56] 0.61    
Diabetesa
No ref    ref   
Yes 5.46 [1.57,18.94] 0.008 7.27 [1.93,27.30] 0.003
Hypertensiona
No ref      
Yes 1.29 [0.84,1.19] 0.37    
Liver Diseasea
No ref      
Yes 1.05 [0.50,2.21] 0.90    
HIVa
No ref      
Yes 0.73 [0.16,3.28] 0.68    
Screening Test
Tuberculin Skin Test ref      
Interferon Gamma Release Assay 1.21 [0.80,1.84] 0.37    
Year of Arrival
2012 ref      
2013 1.50 [0.93,2.41] 0.10    
2014 1.32 [0.79,2.18] 0.29    
2015 1.12 [0.66,1.89] 0.67    
2016 0.99 [0.58,1.70] 0.97    
Family Size at Time of Entry
Single ref    ref   
Family of 2–3 1.36 [0.89,2.07] 0.16 1.18 [0.74,1.87] 0.49
Family of > 3 1.05 [0.71,1.56] 0.80 1.11 [0.70,1.74] 0.66
Sex
Female ref    ref   
Male 1.01 [0.72,1.43] 0.06 1.02 [0.74,1.49] 0.90
Region of Origin
Sub-Saharan Africa ref    ref   
South-eastern Asia 2.10 [1.34,3.29] 0.001 2.30 [1.43,3.70] 0.001
Southern Asia 1.63 [1.05,2.58] 0.03 1.64 [1.02,2.64] 0.04
Western Asia 0.88 [0.44,1.77] 0.72 0.64 [0.29,1.38] 0.25
Other 2.00 [0.84,4.79] 0.12 2.33 [0.92,5.94] 0.08
Smoking History
No ref      
Yes 0.92 [0.47,1.79] 0.80    
Flu Shot Received
No ref    ref   
Yes 1.51 [1.08,2.12] 0.02 1.65 [1.14,2.40] 0.008
Regimen
9H: Isoniazid only ref    ref   
3HP: Isoniazid + Rifapentine 1.33 [.087,2.04] 0.19 1.58 [0.99,2.51] 0.05
4R: Rifampin 1.49 [0.47,4.79] 0.50 1.47 [0.42,5.10] 0.54
Multiple regimens 1.65 [0.75,3.61] 0.21 1.54 [0.68,3.47] 0.30
Time to Appointment, days
Screened after 11 vs 28 days 0.49 [0.28,0.86] 0.01 0.47 [0.26,0.86] 0.01
Screened after 14 vs 28 days 0.61 [0.41,0.91] 0.01 0.48 [0.27,0.86] 0.01
Distance to TB Clinic, miles 0.92 [0.82,1.03] 0.16    
Ageb 1.00 [0.99,1.01] 0.79 1.00 [0.99,1.02] 0.63
  1. aElixhauser Comorbidity Score and individual comorbidities were run in separate models
  2. bOdds expressed as change per one year increase in age