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Table 2 Laboratory data in patients with cryptococcal meningitis

From: The utility of cerebrospinal fluid white cell count during the prognostic assessment for cryptococcal meningitis patients: a retrospective study

Variables All
(N = 150)
Good outcome
(N = 94)
Bad outcome
(N = 56)
P-value
CSF
 WCC (cells/μl), Median (IQR) 60.00 (10.00–140.00) 90.00 (46.00–180.00) 10.00 (0.00–40.00) 0.000
 Total protein (mg/dL), Median (IQR) 0.81 (0.52–1.14) 0.87 (0.61–1.23) 0.65 (0.41–0.91) 0.002
 Glucose (mmol/L), Median (IQR) 1.95 (0.87–2.73) 1.88 (0.80–2.66) 1.99 (0.97–2.96) 0.728
 Chloride (mmol/L), (mean ± SD) 118.75 ± 6.14 118.62 ± 5.70 118.96 ± 6.85 0.345
 Positive India ink stain(%) 120 (80.00%) 66 (70.21%) 54 (96.43%) 0.000
 Positive CSF fungal culture(%) 116 (77.33%) 75 (79.79%) 41 (73.21%) 0.421
 Positive India ink stain & fungal culture(%) 96 (64.00%) 57 (60.64%) 39 (69.64%) 0.295
Serum
 Albumin(g/L), (mean ± SD) 39.73 ± 4.81 40.43 ± 4.33 37.98 ± 5.56 0.025
 WBC (× 109/L), (mean ± SD) 8.35 ± 3.46 8.54 ± 3.20 8.01 ± 3.88 0.364
 Hemoglobin (g/L), (mean ± SD) 124.49 ± 19.66 127.95 ± 20.51 120.02 ± 19.67 0.022
 CD4+ T lymphocyte (%),(mean ± SD)a 25.14 ± 16.75 31.35 ± 14.40 11.97 ± 13.58 0.000
 CD8+ T lymphocyte (%),(mean ± SD)a 34.52 ± 16.80 29.61 ± 13.61 44.92 ± 18.32 0.000
 CD4/CD8 ratio (%), Median (IQR)a 0.93 (0.20–1.57) 1.19 (0.70–1.76) 0.10 (0.03–0.83) 0.000
  1. a47 missing values, CSF cerebrospinal fluid, WCC white cell count, WBC white blood cell