Table 2 Laboratory data in patients with cryptococcal meningitis
Variables | All (N = 150) | Good outcome (N = 94) | Bad outcome (N = 56) | P-value |
|---|---|---|---|---|
CSF | ||||
WCC (cells/μl), Median (IQR) | 60.00 (10.00–140.00) | 90.00 (46.00–180.00) | 10.00 (0.00–40.00) | 0.000 |
Total protein (mg/dL), Median (IQR) | 0.81 (0.52–1.14) | 0.87 (0.61–1.23) | 0.65 (0.41–0.91) | 0.002 |
Glucose (mmol/L), Median (IQR) | 1.95 (0.87–2.73) | 1.88 (0.80–2.66) | 1.99 (0.97–2.96) | 0.728 |
Chloride (mmol/L), (mean ± SD) | 118.75 ± 6.14 | 118.62 ± 5.70 | 118.96 ± 6.85 | 0.345 |
Positive India ink stain(%) | 120 (80.00%) | 66 (70.21%) | 54 (96.43%) | 0.000 |
Positive CSF fungal culture(%) | 116 (77.33%) | 75 (79.79%) | 41 (73.21%) | 0.421 |
Positive India ink stain & fungal culture(%) | 96 (64.00%) | 57 (60.64%) | 39 (69.64%) | 0.295 |
Serum | ||||
Albumin(g/L), (mean ± SD) | 39.73 ± 4.81 | 40.43 ± 4.33 | 37.98 ± 5.56 | 0.025 |
WBC (× 109/L), (mean ± SD) | 8.35 ± 3.46 | 8.54 ± 3.20 | 8.01 ± 3.88 | 0.364 |
Hemoglobin (g/L), (mean ± SD) | 124.49 ± 19.66 | 127.95 ± 20.51 | 120.02 ± 19.67 | 0.022 |
CD4+ T lymphocyte (%),(mean ± SD)a | 25.14 ± 16.75 | 31.35 ± 14.40 | 11.97 ± 13.58 | 0.000 |
CD8+ T lymphocyte (%),(mean ± SD)a | 34.52 ± 16.80 | 29.61 ± 13.61 | 44.92 ± 18.32 | 0.000 |
CD4/CD8 ratio (%), Median (IQR)a | 0.93 (0.20–1.57) | 1.19 (0.70–1.76) | 0.10 (0.03–0.83) | 0.000 |