Table 3 Frequencies of P. falciparum mutant gene haplotypes identified in blood donors
Gene | Total number of mutant haplotypes identified | Percentage mutant haplotypes identified |
|---|---|---|
Pfcrt (n = 77) | ||
 CVIET | 9 | 11.6% |
Pfmdr1 (n = 74) | ||
 NFD | 4 | 5.4% |
 NYY | 4 | 5.4% |
 YFN | 6 | 8.1% |
 NFY | 8 | 10.8% |
Pfdhfr (n = 79) | ||
 Single mutation | ||
  NRSI | 17 | 21.5% |
  NCNI | 20 | 25.3% |
  Double mutation |  |  |
  NRNI | 6 | 7.6% |
  Triple mutation |  |  |
  IRNI | 19 | 24.0% |
Pfdhps (n = 79) | ||
 Single mutation haplotype | ||
  SGKAA | 13 | 16.4% |
 Double mutation haplotype | ||
 AGKAA | 12 | 15.2% |
 Triple mutation haplotype | ||
  AGKAS | 11 | 13.9% |
  AGKSA | 9 | 11.4% |
  FGKAS | 5 | 6.3% |
 Quadruple mutation haplotype | ||
  AGKSS | 5 | 6.3% |
 Quintuple mutation haplotype | ||
 AGESS | 14 | 17.7% |
Kelch 13 (n = 84) | ||
Non-synonymous mutations | ||
  P615L | 4 | 4.8% |
  A578S | 4 | 4.8% |
  C580Y | 3 | 3.6% |
  I543V | 2 | 2.4% |
  A676S | 1 | 1.2% |