Table 2 Clinical characteristics and outcomes associated with TTP in 52 children with P. aeruginosa bacteremia
Characteristics | Early TTP (TTP ≤18 h, n = 21) | Late TTP (TTP >18 h, n = 31) | P values |
|---|---|---|---|
Basic information | |||
 Age(years) (median, IQR) | 0.85(0.48–8.79) | 2.66(0.30–9.01) | 0.911 |
 Male (n, %) | 11(52.4%) | 21(67.7%) | 0.384 |
 Weight(kilogram)(median, IQR) | 8.5(7.5–24.75) | 13.5(6.00–28.00) | 0.668 |
Underlying diseases | |||
 Hematologic malignancies (n, %) | 3(14.3%) | 13(41.9%) | 0.070 |
 Congenital heart disease (n, %) | 3(14.3%) | 3(9.7%) | 0.946 |
Underlying conditions | |||
 Immunosuppression (n, %) | 6(28.6%) | 20(64.5%) | 0.023* |
 Neutropenia (n, %) | 10(47.6%) | 14(45.2%) | 1.000 |
 Hypoalbuminemia (n, %) | 12(57.1%) | 10(32.3%) | 0.093 |
Complications | |||
 Pneumonia (n, %) | 4(19.0%) | 5(16.1%) | 1.000 |
 Meningitis (n, %) | 3(14.3%) | 2(6.5%) | 0.645 |
 Peritonitis | 2(9.5%) | 1(3.2%) | 0.727 |
Origins of infection | |||
 Respiratory tract (n, %) | 11(52.4%) | 11(35.5%) | 0.263 |
 Primary bacteremia (n, %) | 2(9.5%) | 5(16.1%) | 0.787 |
 Vascular-catheter related infection (n, %) | 3(14.3%) | 5(16.7%) | 1.000 |
 Soft tissue infection (n, %) | 2(9.5%) | 6(19.4%) | 0.567 |
 Gastrointestinal infection (n, %) | 3(14.3%) | 2(6.5%) | 0.645 |
 Post-surgery or-procedure bacteremia (n, %) | 0(0.0%) | 2(6.5%) | 0.240 |
Intensive unit care (n, %) | 13(61.9%) | 7(22.6%) | 0.008* |
Nosocomial infection (n, %) | 7(33.3%) | 15(48.4%) | 0.392 |
Pittsburgh bacteremia scores (median, IQR) | 3.00(1.00–5.00) | 1.00(1.00–4.00) | 0.046* |
Antibiotics administration before blood culture (n, %) | 12(57.1%) | 19(61.3%) | 0.781 |
Length of hospitalization days (median, IQR) | 21.04(2.82–41.29) | 28.92(11.92–36.71) | 0.176 |
Multi-drug resistance bacteria (n, %) | 0(0.0%) | 4(12.9%) | 0.090 |
Outcomes | |||
 Septic shock (n, %) | 11(52.4%) | 4(12.9%) | 0.006* |
 In-hospital mortality (n, %) | 9(42.9%) | 3(9.7%) | 0.014* |