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Table 1 Demographic and clinical characteristics of all patients

From: Machine learning reveals that Mycobacterium tuberculosis genotypes and anatomic disease site impacts drug resistance and disease transmission among patients with proven extra-pulmonary tuberculosis

Variable

 

ALL

Lineage of Mycobacterium tuberculosis isolate

P-value

 

Level

N = 70 (%)

Orphan, n = 12 (%)

2

(East Asian); n = 25 (%)

3

(East-African Indian); n = 6 (%)

4

(Euro-American); n = 27 (%)

 

Demographic

 Sex

Female

28 (40%)

5 (42%)

5 (20%)

5 (83%)

13 (48%)

0.021

Male

42 (60%)

7 (58%)

20 (80%)

1 (17%)

14 (52%)

 

 Age

Median (range); years

34 (1–82)

33.5 (12–61)

36 (1–60)

38.5 (32–82)

33 (9–50)

0.492

 Age groups

Pediatric (<16y)

5 (7%)

1 (8%)

3 (12%)

0

1 (4%)

0.684

Adult (>16y)

65 (93%)

11 (92%)

22 (88%)

6 (100%)

26 (96%)

 

 TB/DOTS Facilities

Folang

1 (1%)

0

1 (4%)

0

0

0.328

Kalafong

26 (37%)

4 (33%)

8 (32%)

5 (83%)

9 (33%)

 

Mamelodi

10 (14%)

1 (8%)

2 (8%)

1 (17%)

6 (22%)

 

Potchefstroom

4 (6%)

0

0

0

4 (15%)

 

Pretoria West

4 (6%)

1 (8%)

2 (8%)

0

1 (4%)

 

Skinner

2 (3%)

1 (8%)

0

0

1 (4%)

 

Steve Biko

14 (20%)

3 (33%)

6 (24%)

0

4 (15%)

 

Tshwane

9 (13%)

1 (8%)

6 (24%)

0

2 (7.41%

 

Clinical

 Disease site

Pleural effusion

20 (29)

2 (17)

4 (16)

3 (50)

11 (41)

0.489

Lymphadenitis

20 (29)

4 (33)

11 (44)

1 (17)

4 (15)

 

Cutaneous TB

10 (14)

3 (25)

1 (4)

1 (17)

5 (19)

 

Peritoneal effusion

5 (7)

0

3 (12)

0

2 (7)

 

Meningeal TB

5 (7)

1 (8)

2 (8)

1 (17)

1 (4)

 

Disseminated

4 (6)

1 (8)

2 (8)

0

1 (4)

 

Genitourinary

2 (3)

0

0

0

2 (7)

 

Other

4 (6)

1 (8)

2 (8)

0

1 (4)

 

 DR

RIF/INH susceptible

59 (84)

9 (75)

22 (88)

5 (83)

23 (85)

0.125

RIF monoresistant

6 (9)

3 (25)

0

0

3 (11)

 

INH monoresistant

3 (4)

0

2 (8)

0

1 (4)

 

MDR-TB

2 (3)

0

1 (4)

1 (17)

0

 
  1. RIF Rifampin; INH Isoniazid; MDR-TB Multidrug resistant tuberculosis; DR Drug resistance