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Table 2 Laboratory findings of patients with COVID-19 on admission to hospital

From: Correlation analysis between disease severity and clinical and biochemical characteristics of 143 cases of COVID-19 in Wuhan, China: a descriptive study

  Normal Range Median (IQR)    P Valuea
Total (N = 143) Mild/Moderate (n = 72) Severe/Critical (n = 71)
White blood cell count, × 109/L 3.5–9.5 3.8 (3.2–5.8) 3.6 (3.2–4.4) 4.6 (3.2–7.3) 0.006
Neutrophil count, ×109/L 1.8–6.3 3.7 (2.2–5.6) 3.2 (2.2–4.5) 4.5 (2.4–6.6) 0.005
Lymphocyte count, ×109/L 1.1–3.2 0.9 (0.6–1.2) 1.1 (0.7–1.3) 0.7 (0.6–1.0) 0.000
Monocyte count, × 109/L 0.1–0.6 0.3 (0.2–0.4) 0.3 (0.2–0.4) 0.3 (0.2–0.4) 0.816
Hemoglobin, g/L 115–150 123 (119–133) 124 (119–136) 123 (116–130) 0.118
Platelet count, ×109/L 125–350 155 (128–230) 156 (128–228) 154 (124–236) 0.990
HDL-C, mmol/L 1.29–1.55 0.9 (0.8–1.2) 1.1 (0.9–1.3) 0.9 (0.7–1.0) 0.000
LDL-C, mmol/L < 3.12 2.6 (2.2–3.0) 2.6 (2.1–3.0) 2.7 (2.2–3.0) 0.615
Plasma glucose, mmol/L 3.89–5.83 6.7 (5.7–8.2) 5.8 (5.2–7.5) 7.4 (6.1–9.1) 0.000
Serum sodium, mmol/L 135–145 137.2 (135–140) 138 (136–140) 137 (134–140) 0.119
Serum potassium, mmol/L 3.5–5.5 3.4 (3.2–3.6) 3.5 (3.3–3.6) 3.3 (3.1–3.6) 0.005
Creatinine, μmol/L 44–120 65 (52–76) 61 (51–72) 6 (52–79) 0.175
BUN, mmol/L 2.5–6.7 3.6 (2.7–5.2) 3.5 (2.7–4.8) 4.02 (2.7–5.2) 0.225
TBIL, mmol/L 3.4–20.5 14.4 (10.3–20.0) 13.5 (8.0–16.4) 16.2 (13.4–21.8) 0.000
Albumin, g/L 34–54 36.0 (31.7–39.4) 39.0 (36.9–40.0) 32.0 (30.2–34.0) 0.000
AST, U/L 8–40 51.0 (34.1–72.6) 42.6 (30.3–56.8) 61.0 (43.5–87.0) 0.000
ALT, U/L 5–35 40.0 (22.0–62.4) 35.8 (18.3–46.7) 50.0 (28.8–76.8) 0.002
LDH, U/L 109–245 256 (178–354) 214 (153–257) 321 (256–471) 0.000
CK-MB, U/L 0–25 12.3 (9.8–19.1) 11.5 (9.8–16.7) 12.8 (9.9–20.6) 0.134
D-dimer, ug/mL 0–1 0.5 (0.4–1.5) 0.4 (0.3–0.7) 1.2 (0.5–2.9) 0.000
APTT, s 20–40 27.4 (24–31.5) 26.2 (23.8–31.5) 27.6 (24.2–30.7) 0.477
PT, s 9–14 11.2 (10.8–12.4) 11.1 (10.5–12.3) 11.4 (10.8–12.9) 0.347
ESR, mm/h 0–20 37.4 (18.1–62.4) 25.4 (16.7–48.6) 44.7 (21.4–81.0) 0.001
SAA, mg/L 0.1–10 185.0 (26.1–638.9) 40.6 (13.6–141.0) 477.7 (209–996) 0.000
CRP, mg/L 0–5 15.3 (5.0–69.1) 8.6 (4.7–28.6) 54.8 (11.5–100.5) 0.000
PCT, ng/mL < 0.04     0.000
< 0.04, n (%)   85 (59.4) 55 (76.4) 30 (42.3)  
0.04–0.25, n (%)   39 (27.3) 12 (16.7) 27 (38.0)  
0.25–0.5, n (%)   14 (9.8) 4 (5.6) 10 (14.1)  
≥0.5, n (%)   5 (3.5) 1 (1.4) 4 (5.6)  
  1. Abbreviations: HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, BUN blood urea nitrogen, TBIL total bilirubin, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, CK-MB creatine kinase-muscle and brain type, APTT activated partial thromboplastin time, PT prothrombin time, ESR erythrocyte sedimentation rate, SAA serum amyloid A, CRP C-reactive protein, PCT procalcitonin, IQR interquartile range, COVID-19 Coronavirus disease 2019
  2. aP values indicate differences between mild/moderate and severe/critical. P < 0.05 was considered statistically significant