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Table 2 Laboratory findings of patients with COVID-19 on admission to hospital

From: Correlation analysis between disease severity and clinical and biochemical characteristics of 143 cases of COVID-19 in Wuhan, China: a descriptive study

 

Normal Range

Median (IQR)

  

P Valuea

Total (N = 143)

Mild/Moderate (n = 72)

Severe/Critical (n = 71)

White blood cell count, × 109/L

3.5–9.5

3.8 (3.2–5.8)

3.6 (3.2–4.4)

4.6 (3.2–7.3)

0.006

Neutrophil count, ×109/L

1.8–6.3

3.7 (2.2–5.6)

3.2 (2.2–4.5)

4.5 (2.4–6.6)

0.005

Lymphocyte count, ×109/L

1.1–3.2

0.9 (0.6–1.2)

1.1 (0.7–1.3)

0.7 (0.6–1.0)

0.000

Monocyte count, × 109/L

0.1–0.6

0.3 (0.2–0.4)

0.3 (0.2–0.4)

0.3 (0.2–0.4)

0.816

Hemoglobin, g/L

115–150

123 (119–133)

124 (119–136)

123 (116–130)

0.118

Platelet count, ×109/L

125–350

155 (128–230)

156 (128–228)

154 (124–236)

0.990

HDL-C, mmol/L

1.29–1.55

0.9 (0.8–1.2)

1.1 (0.9–1.3)

0.9 (0.7–1.0)

0.000

LDL-C, mmol/L

< 3.12

2.6 (2.2–3.0)

2.6 (2.1–3.0)

2.7 (2.2–3.0)

0.615

Plasma glucose, mmol/L

3.89–5.83

6.7 (5.7–8.2)

5.8 (5.2–7.5)

7.4 (6.1–9.1)

0.000

Serum sodium, mmol/L

135–145

137.2 (135–140)

138 (136–140)

137 (134–140)

0.119

Serum potassium, mmol/L

3.5–5.5

3.4 (3.2–3.6)

3.5 (3.3–3.6)

3.3 (3.1–3.6)

0.005

Creatinine, μmol/L

44–120

65 (52–76)

61 (51–72)

6 (52–79)

0.175

BUN, mmol/L

2.5–6.7

3.6 (2.7–5.2)

3.5 (2.7–4.8)

4.02 (2.7–5.2)

0.225

TBIL, mmol/L

3.4–20.5

14.4 (10.3–20.0)

13.5 (8.0–16.4)

16.2 (13.4–21.8)

0.000

Albumin, g/L

34–54

36.0 (31.7–39.4)

39.0 (36.9–40.0)

32.0 (30.2–34.0)

0.000

AST, U/L

8–40

51.0 (34.1–72.6)

42.6 (30.3–56.8)

61.0 (43.5–87.0)

0.000

ALT, U/L

5–35

40.0 (22.0–62.4)

35.8 (18.3–46.7)

50.0 (28.8–76.8)

0.002

LDH, U/L

109–245

256 (178–354)

214 (153–257)

321 (256–471)

0.000

CK-MB, U/L

0–25

12.3 (9.8–19.1)

11.5 (9.8–16.7)

12.8 (9.9–20.6)

0.134

D-dimer, ug/mL

0–1

0.5 (0.4–1.5)

0.4 (0.3–0.7)

1.2 (0.5–2.9)

0.000

APTT, s

20–40

27.4 (24–31.5)

26.2 (23.8–31.5)

27.6 (24.2–30.7)

0.477

PT, s

9–14

11.2 (10.8–12.4)

11.1 (10.5–12.3)

11.4 (10.8–12.9)

0.347

ESR, mm/h

0–20

37.4 (18.1–62.4)

25.4 (16.7–48.6)

44.7 (21.4–81.0)

0.001

SAA, mg/L

0.1–10

185.0 (26.1–638.9)

40.6 (13.6–141.0)

477.7 (209–996)

0.000

CRP, mg/L

0–5

15.3 (5.0–69.1)

8.6 (4.7–28.6)

54.8 (11.5–100.5)

0.000

PCT, ng/mL

< 0.04

   

0.000

< 0.04, n (%)

 

85 (59.4)

55 (76.4)

30 (42.3)

 

0.04–0.25, n (%)

 

39 (27.3)

12 (16.7)

27 (38.0)

 

0.25–0.5, n (%)

 

14 (9.8)

4 (5.6)

10 (14.1)

 

≥0.5, n (%)

 

5 (3.5)

1 (1.4)

4 (5.6)

 
  1. Abbreviations: HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, BUN blood urea nitrogen, TBIL total bilirubin, AST aspartate aminotransferase, ALT alanine aminotransferase, LDH lactate dehydrogenase, CK-MB creatine kinase-muscle and brain type, APTT activated partial thromboplastin time, PT prothrombin time, ESR erythrocyte sedimentation rate, SAA serum amyloid A, CRP C-reactive protein, PCT procalcitonin, IQR interquartile range, COVID-19 Coronavirus disease 2019
  2. aP values indicate differences between mild/moderate and severe/critical. P < 0.05 was considered statistically significant