Skip to main content

Table 3 Long-term impact of maternal influenza infection on the offspring: multivariate logistic regression analysis

From: Paradoxical long-term impact of maternal influenza infection on neonates and infants

Infant health screening

Offspring born to control

(n = 1,406,692)

Offspring born to women with a history of influenza (n = 34,614)

p-value

Unadjusted OR (95% CI)

Adjusted ORa (95% CI)

Underweight, No. (%)

 4th (30–42 months)

97,312/979,890 (9.9%)

2351/24,358 (9.7%)

0.1502

0.969 (0.928–1.012)

0.966 (0.925–1.009)

 5th (42–54 months)

69,982/953,954 (7.3%)

1656/23,592 (7.0%)

0.0652

0.954 (0.907–1.004)

0.948 (0.901–0.998)

 6th (54–66 months)

65,354/886,721 (7.4%)

1489/21,609 (6.9%)

0.0076

0.930 (0.882–0.981)

0.926 (0.877–0.976)

 7th (66–80 months)

51,921/624,845 (8.3%)

1134/14,144 (8.0%)

0.2135

0.962 (0.905–1.023)

0.956 (0.899–1.017)

Overweight, No. (%)

 4th (30–42 months)

77,412/979,890 (7.9%)

2031/24,358 (8.3%)

0.0123

1.060 (1.013–1.110)

1.057 (1.009–1.107)

 5th (42–54 months)

113,147/953,954 (11.9%)

2854/23,592 (12.1%)

0.2672

1.023 (0.983–1.064)

1.020 (0.980–1.061)

 6th (54–66 months)

111,473/886,721 (12.6%)

2780/21,609 (12.9%)

0.1984

1.027 (0.986–1.069)

1.025 (0.984–1.067)

 7th (66–80 months)

82,126/624,845 (13.1%)

1969/14,144 (13.9%)

0.0068

1.069 (1.018–1.121)

1.063 (1.013–1.116)

BMI (kg/m2), mean (SD)

 4th (30–42 months)

16.0942 (1.4050)

16.1306 (1.4357)

< 0.0001

  

 5th (42–54 months)

16.0248 (1.4412)

16.0456 (1.4382)

0.0281

  

 6th (54–66 months)

15.9905 (1.6017)

16.0198 (1.6687)

0.0109

  

 7th (66–80 months)

16.1291 (1.8858)

16.1709 (1.8875)

0.0091

  
  1. a Multivariate logistic regression analysis was performed. ORs were adjusted for maternal age, diabetes, hypertension, primiparity, cesarean section, preterm labor, birth weight and neonatal sex
  2. OR odds ratio; CI confidence interval